node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADRB2 | EZR | ENSP00000305372 | ENSP00000338934 | adrenoceptor beta 2, surface | ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis | 0.917 |
ADRB2 | SYNE2 | ENSP00000305372 | ENSP00000350719 | adrenoceptor beta 2, surface | spectrin repeat containing, nuclear envelope 2 | 0.517 |
DMD | UTRN | ENSP00000354923 | ENSP00000356515 | dystrophin | utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) | 0.962 |
EZR | ADRB2 | ENSP00000338934 | ENSP00000305372 | ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis | adrenoceptor beta 2, surface | 0.917 |
EZR | MSN | ENSP00000338934 | ENSP00000353408 | ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis | moesin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage | 0.936 |
EZR | SPTA1 | ENSP00000338934 | ENSP00000357130 | ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | 0.591 |
LCP1 | SPTA1 | ENSP00000315757 | ENSP00000357130 | lymphocyte cytosolic protein 1 (L-plastin); Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69 | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | 0.646 |
MSN | EZR | ENSP00000353408 | ENSP00000338934 | moesin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage | ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis | 0.936 |
MSN | PLEC | ENSP00000353408 | ENSP00000323856 | moesin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage | plectin | 0.689 |
PLEC | MSN | ENSP00000323856 | ENSP00000353408 | plectin | moesin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage | 0.689 |
PLEC | SPTA1 | ENSP00000323856 | ENSP00000357130 | plectin | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | 0.606 |
PLS1 | SPTA1 | ENSP00000336831 | ENSP00000357130 | plastin 1; Actin-bundling protein in the absence of calcium | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | 0.646 |
PLS3 | SPTA1 | ENSP00000348163 | ENSP00000357130 | plastin 3; Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | 0.646 |
SPTA1 | EZR | ENSP00000357130 | ENSP00000338934 | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis | 0.591 |
SPTA1 | LCP1 | ENSP00000357130 | ENSP00000315757 | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | lymphocyte cytosolic protein 1 (L-plastin); Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69 | 0.646 |
SPTA1 | PLEC | ENSP00000357130 | ENSP00000323856 | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | plectin | 0.606 |
SPTA1 | PLS1 | ENSP00000357130 | ENSP00000336831 | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | plastin 1; Actin-bundling protein in the absence of calcium | 0.646 |
SPTA1 | PLS3 | ENSP00000357130 | ENSP00000348163 | spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane | plastin 3; Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia | 0.646 |
SYNE2 | ADRB2 | ENSP00000350719 | ENSP00000305372 | spectrin repeat containing, nuclear envelope 2 | adrenoceptor beta 2, surface | 0.517 |
UTRN | DMD | ENSP00000356515 | ENSP00000354923 | utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) | dystrophin | 0.962 |