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CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal); Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and red [...] (450 aa) | |||
PFAS | phosphoribosylformylglycinamidine synthase (1338 aa) | |||
PKD2L1 | polycystic kidney disease 2-like 1; May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling (805 aa) | |||
RIMS2 | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein (1349 aa) |