node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CGN | MYH1 | ENSP00000271636 | ENSP00000226207 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 1, skeletal muscle, adult; Muscle contraction | 0.800 |
CGN | MYH10 | ENSP00000271636 | ENSP00000269243 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 | 0.800 |
CGN | MYH11 | ENSP00000271636 | ENSP00000379616 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 11, smooth muscle; Muscle contraction | 0.800 |
CGN | MYH13 | ENSP00000271636 | ENSP00000252172 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 13, skeletal muscle; Muscle contraction | 0.800 |
CGN | MYH14 | ENSP00000271636 | ENSP00000262269 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 14, non-muscle | 0.867 |
CGN | MYH15 | ENSP00000271636 | ENSP00000273353 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.800 |
CGN | MYH2 | ENSP00000271636 | ENSP00000245503 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 2, skeletal muscle, adult; Muscle contraction. Required for cytoskeleton organization (By similarity) | 0.800 |
CGN | MYH3 | ENSP00000271636 | ENSP00000226209 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 3, skeletal muscle, embryonic; Muscle contraction | 0.800 |
CGN | MYH4 | ENSP00000271636 | ENSP00000255381 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 4, skeletal muscle; Muscle contraction | 0.800 |
CGN | MYH6 | ENSP00000271636 | ENSP00000348634 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 6, cardiac muscle, alpha; Muscle contraction | 0.800 |
CGN | MYH7 | ENSP00000271636 | ENSP00000347507 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 7, cardiac muscle, beta | 0.800 |
CGN | MYH7B | ENSP00000271636 | ENSP00000262873 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 7B, cardiac muscle, beta; Involved in muscle contraction | 0.800 |
CGN | MYH9 | ENSP00000271636 | ENSP00000216181 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping | 0.805 |
HSP90AA1 | HSP90AB1 | ENSP00000335153 | ENSP00000325875 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | 0.999 |
HSP90AA1 | MYH1 | ENSP00000335153 | ENSP00000226207 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 1, skeletal muscle, adult; Muscle contraction | 0.744 |
HSP90AA1 | MYH10 | ENSP00000335153 | ENSP00000269243 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 | 0.744 |
HSP90AA1 | MYH11 | ENSP00000335153 | ENSP00000379616 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 11, smooth muscle; Muscle contraction | 0.760 |
HSP90AA1 | MYH13 | ENSP00000335153 | ENSP00000252172 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 13, skeletal muscle; Muscle contraction | 0.740 |
HSP90AA1 | MYH14 | ENSP00000335153 | ENSP00000262269 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 14, non-muscle | 0.837 |
HSP90AA1 | MYH15 | ENSP00000335153 | ENSP00000273353 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.740 |