node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAT | UBC | ENSP00000241052 | ENSP00000344818 | catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells | ubiquitin C | 0.866 |
COX11 | COX15 | ENSP00000299335 | ENSP00000016171 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | 0.926 |
COX11 | COX17 | ENSP00000299335 | ENSP00000261070 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | 0.891 |
COX11 | LACE1 | ENSP00000299335 | ENSP00000357973 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | lactation elevated 1 | 0.426 |
COX11 | MT-CO2 | ENSP00000299335 | ENSP00000354876 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) | 0.880 |
COX11 | SCO1 | ENSP00000299335 | ENSP00000255390 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | SCO1 cytochrome c oxidase assembly protein; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX | 0.942 |
COX15 | COX11 | ENSP00000016171 | ENSP00000299335 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.926 |
COX15 | COX17 | ENSP00000016171 | ENSP00000261070 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | 0.761 |
COX15 | MT-CO2 | ENSP00000016171 | ENSP00000354876 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) | 0.711 |
COX15 | SCO1 | ENSP00000016171 | ENSP00000255390 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | SCO1 cytochrome c oxidase assembly protein; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX | 0.935 |
COX15 | UBC | ENSP00000016171 | ENSP00000344818 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | ubiquitin C | 0.627 |
COX17 | COX11 | ENSP00000261070 | ENSP00000299335 | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.891 |
COX17 | COX15 | ENSP00000261070 | ENSP00000016171 | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | 0.761 |
COX17 | MT-CO2 | ENSP00000261070 | ENSP00000354876 | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) | 0.753 |
COX17 | SCO1 | ENSP00000261070 | ENSP00000255390 | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | SCO1 cytochrome c oxidase assembly protein; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX | 0.945 |
LACE1 | COX11 | ENSP00000357973 | ENSP00000299335 | lactation elevated 1 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.426 |
MT-CO2 | COX11 | ENSP00000354876 | ENSP00000299335 | mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.880 |
MT-CO2 | COX15 | ENSP00000354876 | ENSP00000016171 | mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | 0.711 |
MT-CO2 | COX17 | ENSP00000354876 | ENSP00000261070 | mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) | cytochrome c oxidase assembly homolog 17 (yeast); Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) | 0.753 |
MT-CO2 | SCO1 | ENSP00000354876 | ENSP00000255390 | mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) | SCO1 cytochrome c oxidase assembly protein; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX | 0.993 |