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MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) (540 aa) | |||
KLRB1 | killer cell lectin-like receptor subfamily B, member 1; Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediat [...] (225 aa) | |||
ADAMDEC1 | ADAM-like, decysin 1; May play an important role in the control of the immune response and during pregnancy (By similarity) (470 aa) | |||
REG4 | regenerating islet-derived family, member 4; Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium (158 aa) | |||
CD72 | CD72 molecule; Plays a role in B-cell proliferation and differentiation (359 aa) | |||
CLEC2D | C-type lectin domain family 2, member D; Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans (194 aa) | |||
MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity) (675 aa) | |||
FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23); Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen) (321 aa) | |||
MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (552 aa) | |||
CLEC1B | C-type lectin domain family 1, member B; Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets (229 aa) | |||
CLEC7A | C-type lectin domain family 7, member A (247 aa) | |||
REG3A | regenerating islet-derived 3 alpha; Binds to Gram-positive bacteria and restricts their association with the small intestinal epithelial surface. Consequently, limits the activation of adaptive immune responses by the microbiota (By similarity). Mannan- and peptidoglycan- binding lectin. In vitro, may have some direct antibacterial activity against Gram-positive enteric microbes (PubMed-16931762) (175 aa) | |||
CLEC4G | C-type lectin domain family 4, member G (293 aa) | |||
SELE | selectin E; Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis (610 aa) | |||
MPP7 | membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7); Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact (576 aa) | |||
CLEC12B | C-type lectin domain family 12, member B; Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases (276 aa) | |||
CLEC12A | C-type lectin domain family 12, member A; Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases (275 aa) | |||
MPP1 | membrane protein, palmitoylated 1, 55kDa; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity) (466 aa) | |||
CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) (921 aa) | |||
MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (585 aa) | |||
SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (3571 aa) | |||
MPP4 | membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4); May play a role in retinal photoreceptors development (By similarity) (637 aa) | |||
ACAN | aggrecan; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region (2530 aa) | |||
LY75-CD302 | LY75-CD302 readthrough (1873 aa) | |||
CLEC5A | C-type lectin domain family 5, member A; Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release (188 aa) | |||
LY75 | lymphocyte antigen 75; Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes (1873 aa) |