node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYSTM1 | IER3IP1 | ENSP00000261811 | ENSP00000256433 | cysteine-rich transmembrane module containing 1 | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | 0.644 |
ELAVL1 | PTBP3 | ENSP00000385269 | ENSP00000334499 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro | polypyrimidine tract binding protein 3 | 0.509 |
ELAVL1 | UBC | ENSP00000385269 | ENSP00000344818 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro | ubiquitin C | 0.998 |
FAM3C | IER3IP1 | ENSP00000353025 | ENSP00000256433 | family with sequence similarity 3, member C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | 0.644 |
IER3IP1 | CYSTM1 | ENSP00000256433 | ENSP00000261811 | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | cysteine-rich transmembrane module containing 1 | 0.644 |
IER3IP1 | FAM3C | ENSP00000256433 | ENSP00000353025 | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | family with sequence similarity 3, member C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition | 0.644 |
IER3IP1 | UBC | ENSP00000256433 | ENSP00000344818 | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | ubiquitin C | 0.899 |
IER3IP1 | YIPF5 | ENSP00000256433 | ENSP00000274496 | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | Yip1 domain family, member 5; Plays a role in transport between endoplasmic reticulum and Golgi | 0.877 |
IER3IP1 | YIPF6 | ENSP00000256433 | ENSP00000417573 | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | Yip1 domain family, member 6 | 0.425 |
IER3IP1 | YIPF7 | ENSP00000256433 | ENSP00000332772 | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | Yip1 domain family, member 7 | 0.747 |
PTBP3 | ELAVL1 | ENSP00000334499 | ENSP00000385269 | polypyrimidine tract binding protein 3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro | 0.509 |
PTBP3 | UBC | ENSP00000334499 | ENSP00000344818 | polypyrimidine tract binding protein 3 | ubiquitin C | 0.942 |
TRAF6 | UBC | ENSP00000337853 | ENSP00000344818 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | ubiquitin C | 0.999 |
UBC | ELAVL1 | ENSP00000344818 | ENSP00000385269 | ubiquitin C | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro | 0.998 |
UBC | IER3IP1 | ENSP00000344818 | ENSP00000256433 | ubiquitin C | immediate early response 3 interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) | 0.899 |
UBC | PTBP3 | ENSP00000344818 | ENSP00000334499 | ubiquitin C | polypyrimidine tract binding protein 3 | 0.942 |
UBC | TRAF6 | ENSP00000344818 | ENSP00000337853 | ubiquitin C | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | 0.999 |
UBC | YIF1A | ENSP00000344818 | ENSP00000366098 | ubiquitin C | Yip1 interacting factor homolog A (S. cerevisiae); Possible role in transport between endoplasmic reticulum and Golgi | 0.828 |
UBC | YIF1B | ENSP00000344818 | ENSP00000343435 | ubiquitin C | Yip1 interacting factor homolog B (S. cerevisiae) | 0.824 |
YIF1A | UBC | ENSP00000366098 | ENSP00000344818 | Yip1 interacting factor homolog A (S. cerevisiae); Possible role in transport between endoplasmic reticulum and Golgi | ubiquitin C | 0.828 |