Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | MRPL32 | mitochondrial ribosomal protein L32 (188 aa) | ||
 | C1QBP | complement component 1, q subcomponent binding protein; Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades. Putative receptor for C1q; specifically binds to the globular "heads" of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93. In complex with cytokera [...] (282 aa) | ||
 | MRPL51 | mitochondrial ribosomal protein L51 (128 aa) | ||
 | MPV17 | MpV17 mitochondrial inner membrane protein; Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance (176 aa) | ||
 | TP53I3 | tumor protein p53 inducible protein 3; May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro) (332 aa) | ||
 | SYNJ2BP | synaptojanin 2 binding protein (145 aa) | ||
 | MRPL44 | mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome (332 aa) | ||
 | ABI2 | abl-interactor 2; May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA (475 aa) | ||
 | SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) (226 aa) | ||
 | ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) (838 aa) | ||
 | TMEM177 | transmembrane protein 177 (311 aa) | ||
 | HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA (825 aa) | ||
 | TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae); Required during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (804 aa) | ||
 | MRPL39 | mitochondrial ribosomal protein L39 (353 aa) | ||
 | MRPL13 | mitochondrial ribosomal protein L13 (178 aa) | ||
 | MRPL38 | mitochondrial ribosomal protein L38 (380 aa) | ||
 | UBC | ubiquitin C (685 aa) | ||
 | MRPL37 | mitochondrial ribosomal protein L37 (423 aa) | ||
 | MRPL24 | mitochondrial ribosomal protein L24 (216 aa) | ||
 | MRPL9 | mitochondrial ribosomal protein L9 (267 aa) | ||
 | MRPL50 | mitochondrial ribosomal protein L50 (158 aa) | ||
 | MRPL19 | mitochondrial ribosomal protein L19 (292 aa) | ||
 | ILF3 | interleukin enhancer binding factor 3, 90kDa (898 aa) | ||
 | MRPL47 | mitochondrial ribosomal protein L47 (250 aa) | ||
 | MRPL42 | mitochondrial ribosomal protein L42 (142 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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