node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C14orf166 | C22orf28 | ENSP00000261700 | ENSP00000216038 | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | 0.999 |
C14orf166 | C2orf49 | ENSP00000261700 | ENSP00000258457 | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | chromosome 2 open reading frame 49 | 0.999 |
C14orf166 | DDX1 | ENSP00000261700 | ENSP00000233084 | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | 0.999 |
C14orf166 | FAM98B | ENSP00000261700 | ENSP00000380734 | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | family with sequence similarity 98, member B | 0.999 |
C22orf28 | C14orf166 | ENSP00000216038 | ENSP00000261700 | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | 0.999 |
C22orf28 | C2orf49 | ENSP00000216038 | ENSP00000258457 | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | chromosome 2 open reading frame 49 | 0.999 |
C22orf28 | DDX1 | ENSP00000216038 | ENSP00000233084 | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | 0.997 |
C22orf28 | FAM98B | ENSP00000216038 | ENSP00000380734 | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | family with sequence similarity 98, member B | 0.999 |
C2orf49 | C14orf166 | ENSP00000258457 | ENSP00000261700 | chromosome 2 open reading frame 49 | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | 0.999 |
C2orf49 | C22orf28 | ENSP00000258457 | ENSP00000216038 | chromosome 2 open reading frame 49 | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | 0.999 |
C2orf49 | DDX1 | ENSP00000258457 | ENSP00000233084 | chromosome 2 open reading frame 49 | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | 0.992 |
C2orf49 | FAM98B | ENSP00000258457 | ENSP00000380734 | chromosome 2 open reading frame 49 | family with sequence similarity 98, member B | 0.999 |
DDX1 | C14orf166 | ENSP00000233084 | ENSP00000261700 | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | 0.999 |
DDX1 | C22orf28 | ENSP00000233084 | ENSP00000216038 | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | 0.997 |
DDX1 | C2orf49 | ENSP00000233084 | ENSP00000258457 | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | chromosome 2 open reading frame 49 | 0.992 |
DDX1 | FAM98B | ENSP00000233084 | ENSP00000380734 | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | family with sequence similarity 98, member B | 0.998 |
FAM98B | C14orf166 | ENSP00000380734 | ENSP00000261700 | family with sequence similarity 98, member B | chromosome 14 open reading frame 166; Involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication | 0.999 |
FAM98B | C22orf28 | ENSP00000380734 | ENSP00000216038 | family with sequence similarity 98, member B | chromosome 22 open reading frame 28; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3’,5’- phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs | 0.999 |
FAM98B | C2orf49 | ENSP00000380734 | ENSP00000258457 | family with sequence similarity 98, member B | chromosome 2 open reading frame 49 | 0.999 |
FAM98B | DDX1 | ENSP00000380734 | ENSP00000233084 | family with sequence similarity 98, member B | DEAD (Asp-Glu-Ala-Asp) box helicase 1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5’ single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 ex [...] | 0.998 |