block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

DEAD (Asp-Glu-Ala-Asp) box helicase 21; Can unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase). Functions as cofactor for JUN-activated transcription. Involved in rRNA processing

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

DEAD (Asp-Glu-Ala-Asp) box polypeptide 27

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

DEAD (Asp-Glu-Ala-Asp) box helicase 56; May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

guanine nucleotide binding protein-like 3 (nucleolar); May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity)

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

guanine nucleotide binding protein-like 3 (nucleolar)-like; Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal pr [...]

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity)

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

KIAA0020

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

MKI67 (FHA domain) interacting nucleolar phosphoprotein

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By similarity)

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

NOP2/Sun domain family, member 6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential)

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

ribosome production factor 2 homolog (S. cerevisiae)

block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA (By similarity)