7 items (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	RBP2	retinol binding protein 2, cellular; Intracellular transport of retinol (134 aa)
	CLPS	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase (112 aa)
	PNLIPRP1	pancreatic lipase-related protein 1; May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity) (467 aa)
	PNLIP	pancreatic lipase (465 aa)
	PNLIPRP3	pancreatic lipase-related protein 3 (467 aa)
	CEL	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides (756 aa)
	LIPF	lipase, gastric (408 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEL	CLPS	ENSP00000361151	ENSP00000259938	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	0.927
CEL	LIPF	ENSP00000361151	ENSP00000377900	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	lipase, gastric	0.916
CEL	PNLIP	ENSP00000361151	ENSP00000358223	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	pancreatic lipase	0.979
CEL	PNLIPRP1	ENSP00000361151	ENSP00000351695	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	pancreatic lipase-related protein 1; May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity)	0.628
CEL	PNLIPRP3	ENSP00000361151	ENSP00000358232	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	pancreatic lipase-related protein 3	0.900
CLPS	CEL	ENSP00000259938	ENSP00000361151	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	0.927
CLPS	LIPF	ENSP00000259938	ENSP00000377900	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	lipase, gastric	0.576
CLPS	PNLIP	ENSP00000259938	ENSP00000358223	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	pancreatic lipase	0.992
CLPS	PNLIPRP1	ENSP00000259938	ENSP00000351695	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	pancreatic lipase-related protein 1; May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity)	0.630
CLPS	PNLIPRP3	ENSP00000259938	ENSP00000358232	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	pancreatic lipase-related protein 3	0.812
CLPS	RBP2	ENSP00000259938	ENSP00000232217	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	retinol binding protein 2, cellular; Intracellular transport of retinol	0.900
LIPF	CEL	ENSP00000377900	ENSP00000361151	lipase, gastric	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	0.916
LIPF	CLPS	ENSP00000377900	ENSP00000259938	lipase, gastric	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	0.576
LIPF	PNLIP	ENSP00000377900	ENSP00000358223	lipase, gastric	pancreatic lipase	0.973
LIPF	PNLIPRP3	ENSP00000377900	ENSP00000358232	lipase, gastric	pancreatic lipase-related protein 3	0.900
PNLIP	CEL	ENSP00000358223	ENSP00000361151	pancreatic lipase	carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides	0.979
PNLIP	CLPS	ENSP00000358223	ENSP00000259938	pancreatic lipase	colipase, pancreatic; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	0.992
PNLIP	LIPF	ENSP00000358223	ENSP00000377900	pancreatic lipase	lipase, gastric	0.973
PNLIP	PNLIPRP3	ENSP00000358223	ENSP00000358232	pancreatic lipase	pancreatic lipase-related protein 3	0.901
PNLIP	RBP2	ENSP00000358223	ENSP00000232217	pancreatic lipase	retinol binding protein 2, cellular; Intracellular transport of retinol	0.911

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