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MRPL10 MRPL10 UBA52 UBA52 MRPL11 MRPL11 MRPL14 MRPL14 MRPL16 MRPL16 MRPL27 MRPL27 MRPL9 MRPL9 MRPL33 MRPL33 MRPL13 MRPL13 MRPL47 MRPL47 MRPL55 MRPL55 MRPL49 MRPL49 MRPL19 MRPL19 MRPL15 MRPL15 MRPL46 MRPL46 MRPL41 MRPL41 MRPL39 MRPL39 MRPL40 MRPL40 MRPL32 MRPL32 MRPL38 MRPL38 MRP63 MRP63 DLST DLST MRPL50 MRPL50 COX15 COX15 OGDH OGDH CYC1 CYC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
COX15cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A (410 aa)
OGDHoxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components- 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (1023 aa)
MRPL32mitochondrial ribosomal protein L32 (188 aa)
MRPL27mitochondrial ribosomal protein L27 (148 aa)
MRPL15mitochondrial ribosomal protein L15 (296 aa)
MRPL49mitochondrial ribosomal protein L49 (166 aa)
MRPL10mitochondrial ribosomal protein L10 (271 aa)
MRPL33mitochondrial ribosomal protein L33 (65 aa)
MRPL16mitochondrial ribosomal protein L16; Component of the large subunit of mitochondrial ribosome (251 aa)
MRPL39mitochondrial ribosomal protein L39 (353 aa)
MRPL13mitochondrial ribosomal protein L13 (178 aa)
MRPL38mitochondrial ribosomal protein L38 (380 aa)
MRPL11mitochondrial ribosomal protein L11 (192 aa)
MRP63mitochondrial ribosomal protein 63 (102 aa)
MRPL46mitochondrial ribosomal protein L46 (279 aa)
CYC1cytochrome c-1; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain (325 aa)
MRPL40mitochondrial ribosomal protein L40 (206 aa)
DLSTdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components- 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (453 aa)
MRPL55mitochondrial ribosomal protein L55 (164 aa)
MRPL9mitochondrial ribosomal protein L9 (267 aa)
MRPL41mitochondrial ribosomal protein L41; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa)
MRPL14mitochondrial ribosomal protein L14; Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable) (145 aa)
MRPL50mitochondrial ribosomal protein L50 (158 aa)
MRPL19mitochondrial ribosomal protein L19 (292 aa)
UBA52ubiquitin A-52 residue ribosomal protein fusion product 1 (128 aa)
MRPL47mitochondrial ribosomal protein L47 (250 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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