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MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) (540 aa) | |||
RFPL3 | ret finger protein-like 3 (317 aa) | |||
CARD10 | caspase recruitment domain family, member 10; Activates NF-kappa-B via BCL10 and IKK (1032 aa) | |||
CCBL2 | cysteine conjugate-beta lyase 2 (454 aa) | |||
ASNSD1 | asparagine synthetase domain containing 1 (643 aa) | |||
MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity) (675 aa) | |||
ACCS | 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional); Does not catalyze the synthesis of 1-aminocyclopropane- 1-carboxylate but is capable of catalyzing the deamination of L- vinylglycine (501 aa) | |||
MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (552 aa) | |||
LRGUK | leucine-rich repeats and guanylate kinase domain containing (825 aa) | |||
CCBL1 | cysteine conjugate-beta lyase, cytoplasmic; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta- elimination of S-conjugates and Se-conjugates of L- (seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (422 aa) | |||
IMPDH2 | IMP (inosine 5’-monophosphate) dehydrogenase 2; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors (514 aa) | |||
MPP7 | membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7); Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact (576 aa) | |||
CARD14 | caspase recruitment domain family, member 14; Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10 (1004 aa) | |||
GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2; Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate (523 aa) | |||
DLG1 | discs, large homolog 1 (Drosophila) (926 aa) | |||
TAT | tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine (454 aa) | |||
GUK1 | guanylate kinase 1; Essential for recycling GMP and indirectly, cGMP (241 aa) | |||
MPP1 | membrane protein, palmitoylated 1, 55kDa; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity) (466 aa) | |||
ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 (795 aa) | |||
DLG3 | discs, large homolog 3 (Drosophila); Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling (817 aa) | |||
DLG2 | discs, large homolog 2 (Drosophila); Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity) (975 aa) | |||
CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) (921 aa) | |||
ACCSL | 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like (568 aa) | |||
GPT | glutamic-pyruvate transaminase (alanine aminotransferase); Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity) (496 aa) | |||
MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) (585 aa) | |||
MPP4 | membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4); May play a role in retinal photoreceptors development (By similarity) (637 aa) |