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STRINGSTRING
CCDC33 CCDC33 ZBTB8A ZBTB8A DIP2A DIP2A ZNF408 ZNF408 PRDM14 PRDM14 ZNF398 ZNF398 GPATCH2L GPATCH2L ZBTB48 ZBTB48 ZNF263 ZNF263 ZNF165 ZNF165 TRIM41 TRIM41 ZNF473 ZNF473
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
ZNF263zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor (683 aa)
GPATCH2LG patch domain containing 2-like (482 aa)
ZNF473zinc finger protein 473; Involved in histone 3’-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3’-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases (871 aa)
PRDM14PR domain containing 14; Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels- the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5’-GGT [...] (571 aa)
ZNF408zinc finger protein 408; May be involved in transcriptional regulation (720 aa)
TRIM41tripartite motif containing 41; Functions as an E3 ligase that catalyzes the ubiquitin- mediated degradation of protein kinase C (630 aa)
ZBTB8Azinc finger and BTB domain containing 8A; May be involved in transcriptional regulation (441 aa)
ZNF165zinc finger protein 165; May be involved in transcriptional regulation (485 aa)
ZBTB48zinc finger and BTB domain containing 48; Binds to and regulates the J and/or S elements in MHC II promoter (688 aa)
CCDC33coiled-coil domain containing 33 (755 aa)
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila); May provide positional cues for axon pathfinding and patterning in the central nervous system (1571 aa)
ZNF398zinc finger protein 398; Function as a transcriptional activator (642 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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