node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COA6 | COX10 | ENSP00000355572 | ENSP00000261643 | cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae) | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | 0.562 |
COA6 | MT-CO1 | ENSP00000355572 | ENSP00000354499 | cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae) | mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) | 0.719 |
COX10 | COA6 | ENSP00000261643 | ENSP00000355572 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae) | 0.562 |
COX10 | COX11 | ENSP00000261643 | ENSP00000299335 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.947 |
COX10 | COX15 | ENSP00000261643 | ENSP00000016171 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | 0.998 |
COX10 | COX6B1 | ENSP00000261643 | ENSP00000246554 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous); Connects the two COX monomers into the physiological dimeric form (By similarity) | 0.725 |
COX10 | FECH | ENSP00000261643 | ENSP00000372326 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) | 0.939 |
COX10 | HCCS | ENSP00000261643 | ENSP00000326579 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | holocytochrome c synthase; Links covalently the heme group to the apoprotein of cytochrome c (By similarity) | 0.932 |
COX10 | MT-CO1 | ENSP00000261643 | ENSP00000354499 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) | 0.979 |
COX10 | SURF1 | ENSP00000261643 | ENSP00000361042 | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | surfeit 1; Probably involved in the biogenesis of the COX complex | 0.967 |
COX11 | COX10 | ENSP00000299335 | ENSP00000261643 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | 0.947 |
COX11 | COX15 | ENSP00000299335 | ENSP00000016171 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | 0.926 |
COX11 | MT-CO1 | ENSP00000299335 | ENSP00000354499 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) | 0.776 |
COX11 | SURF1 | ENSP00000299335 | ENSP00000361042 | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | surfeit 1; Probably involved in the biogenesis of the COX complex | 0.856 |
COX15 | COX10 | ENSP00000016171 | ENSP00000261643 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | 0.998 |
COX15 | COX11 | ENSP00000016171 | ENSP00000299335 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) | 0.926 |
COX15 | COX6B1 | ENSP00000016171 | ENSP00000246554 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous); Connects the two COX monomers into the physiological dimeric form (By similarity) | 0.662 |
COX15 | MT-CO1 | ENSP00000016171 | ENSP00000354499 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) | 0.729 |
COX15 | SURF1 | ENSP00000016171 | ENSP00000361042 | cytochrome c oxidase assembly homolog 15 (yeast); May be involved in the biosynthesis of heme A | surfeit 1; Probably involved in the biogenesis of the COX complex | 0.916 |
COX6B1 | COX10 | ENSP00000246554 | ENSP00000261643 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous); Connects the two COX monomers into the physiological dimeric form (By similarity) | cytochrome c oxidase assembly homolog 10 (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (By similarity) | 0.725 |