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CNOT2 | CCR4-NOT transcription complex, subunit 2; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may s [...] (540 aa) | |||
KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast); Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity) (381 aa) | |||
MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (681 aa) | |||
IMP4 | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (291 aa) | |||
UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (597 aa) | |||
RBM19 | RNA binding motif protein 19; Plays a role in embryo pre-implantation development (By similarity) (960 aa) | |||
NOP9 | NOP9 nucleolar protein homolog (yeast) (636 aa) | |||
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) (919 aa) | |||
UTP15 | UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (518 aa) | |||
NOL6 | nucleolar protein family 6 (RNA-associated) (1146 aa) | |||
WDR3 | WD repeat domain 3 (943 aa) | |||
UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast); Involved in rRNA-processing and ribosome biogenesis (By similarity) (249 aa) | |||
WDR75 | WD repeat domain 75 (830 aa) | |||
CIRH1A | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV (686 aa) | |||
UBC | ubiquitin C (685 aa) | |||
HEATR1 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) (2144 aa) | |||
PDCD11 | programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA (1871 aa) | |||
RPF1 | ribosome production factor 1 homolog (S. cerevisiae); May be required for ribosome biogenesis (349 aa) | |||
BMS1 | BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (1282 aa) | |||
WDR46 | WD repeat domain 46 (610 aa) | |||
RBM34 | RNA binding motif protein 34 (430 aa) | |||
FTSJ3 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation (847 aa) | |||
SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] (95 aa) | |||
AGAP10 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential) (703 aa) | |||
ENSG00000248354 | Uncharacterized protein (205 aa) | |||
TBL3 | transducin (beta)-like 3 (808 aa) |