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STRINGSTRING
SSR1 SSR1 RPS28 RPS28 RPL30 RPL30 RPL37 RPL37 RPL8 RPL8 RPS3A RPS3A RPL26 RPL26 SSR3 SSR3 RPS21 RPS21 RPN2 RPN2 UBA52 UBA52 SPCS1 SPCS1 RPS29 RPS29 RPS23 RPS23 TRAM1 TRAM1 RPL4 RPL4 RPL35 RPL35 RPL11 RPL11 RPLP2 RPLP2 RPL23 RPL23 RPL41 RPL41 RPS27 RPS27 RPL18 RPL18 RPS16 RPS16 RPS2 RPS2 RPL17 RPL17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
SPCS1signal peptidase complex subunit 1 homolog (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) (169 aa)
RPN2ribophorin II; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (631 aa)
SSR1signal sequence receptor, alpha (286 aa)
RPS16ribosomal protein S16 (146 aa)
RPL35ribosomal protein L35 (123 aa)
TRAM1translocation associated membrane protein 1; Stimulatory or required for the translocation of secretory proteins across the ER membrane (374 aa)
RPL8ribosomal protein L8 (257 aa)
SSR3signal sequence receptor, gamma (translocon-associated protein gamma); TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins (185 aa)
RPL37ribosomal protein L37; Binds to the 23S rRNA (By similarity) (97 aa)
RPL30ribosomal protein L30 (115 aa)
RPL26ribosomal protein L26 (145 aa)
RPS23ribosomal protein S23 (143 aa)
RPL4ribosomal protein L4 (427 aa)
RPLP2ribosomal protein, large, P2; Plays an important role in the elongation step of protein synthesis (115 aa)
RPS2ribosomal protein S2 (293 aa)
RPS21ribosomal protein S21 (83 aa)
RPS3Aribosomal protein S3A; May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity) (264 aa)
RPS27ribosomal protein S27 (84 aa)
RPL11ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) (178 aa)
RPL23ribosomal protein L23 (140 aa)
RPS29ribosomal protein S29 (67 aa)
UBA52ubiquitin A-52 residue ribosomal protein fusion product 1 (128 aa)
RPL41ribosomal protein L41 (25 aa)
RPL18ribosomal protein L18 (188 aa)
RPL17ribosomal protein L17 (184 aa)
RPS28ribosomal protein S28 (69 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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