armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

cadherin 15, type 1, M-cadherin (myotubule); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity)

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

cadherin-related 23; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

cadherin 4, type 1, R-cadherin (retinal); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

catenin (cadherin-associated protein), beta 1, 88kDa; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation [...]

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

dachsous 1 (Drosophila); Calcium-dependent cell-adhesion protein (Potential)

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

dachsous 2 (Drosophila); Calcium-dependent cell-adhesion protein (By similarity)

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

erbb2 interacting protein

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

FAT tumor suppressor homolog 1 (Drosophila); Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact (By similarity)

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

FAT tumor suppressor homolog 2 (Drosophila); Plays a role in the migration of epidermal cells. May modulate the extracellular space surronding parallel fibers of cerebellar during development (By similarity)

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

FAT tumor suppressor homolog 3 (Drosophila); May play a role in the interactions between neurites derived from specific subsets of neurons during development (By similarity)

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

FAT tumor suppressor homolog 4 (Drosophila); May function in the regulation of planar cell polarity (By similarity). Cadherins are cell-cell interaction molecules (By similarity)

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

ras homolog family member A; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disor [...]

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

ras homolog family member B; Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular develo [...]

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

ras homolog family member C; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

tight junction protein 1; The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells

cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7

armadillo repeat gene deleted in velocardiofacial syndrome; Involved in protein-protein interactions at adherens junctions

cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7

cadherin 13, H-cadherin (heart); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth

cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7

cadherin 15, type 1, M-cadherin (myotubule); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation