6 items (Homo sapiens) - STRING network view

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

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Your Input:
	IFT81	intraflagellar transport 81 homolog (Chlamydomonas); Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity) (676 aa)
	TTC21B	tetratricopeptide repeat domain 21B (1316 aa)
	IFT46	intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity) (355 aa)
	SH3D19	SH3 domain containing 19; May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization (790 aa)
	IFT88	intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity) (833 aa)
	TTC21A	tetratricopeptide repeat domain 21A (1320 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFT46	IFT81	ENSP00000264020	ENSP00000242591	intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity)	intraflagellar transport 81 homolog (Chlamydomonas); Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity)	0.742
IFT46	IFT88	ENSP00000264020	ENSP00000323580	intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity)	intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity)	0.806
IFT46	TTC21B	ENSP00000264020	ENSP00000243344	intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity)	tetratricopeptide repeat domain 21B	0.702
IFT81	IFT46	ENSP00000242591	ENSP00000264020	intraflagellar transport 81 homolog (Chlamydomonas); Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity)	intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity)	0.742
IFT81	IFT88	ENSP00000242591	ENSP00000323580	intraflagellar transport 81 homolog (Chlamydomonas); Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity)	intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity)	0.897
IFT81	TTC21B	ENSP00000242591	ENSP00000243344	intraflagellar transport 81 homolog (Chlamydomonas); Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity)	tetratricopeptide repeat domain 21B	0.707
IFT88	IFT46	ENSP00000323580	ENSP00000264020	intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity)	intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity)	0.806
IFT88	IFT81	ENSP00000323580	ENSP00000242591	intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity)	intraflagellar transport 81 homolog (Chlamydomonas); Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity)	0.897
IFT88	TTC21B	ENSP00000323580	ENSP00000243344	intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity)	tetratricopeptide repeat domain 21B	0.817
TTC21B	IFT46	ENSP00000243344	ENSP00000264020	tetratricopeptide repeat domain 21B	intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity)	0.702
TTC21B	IFT81	ENSP00000243344	ENSP00000242591	tetratricopeptide repeat domain 21B	intraflagellar transport 81 homolog (Chlamydomonas); Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity)	0.707
TTC21B	IFT88	ENSP00000243344	ENSP00000323580	tetratricopeptide repeat domain 21B	intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity)	0.817

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