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CALML5 CALML5 SCGN SCGN SPATA21 SPATA21 EFCAB7 EFCAB7 EFCAB6 EFCAB6 MMADHC MMADHC MMACHC MMACHC PVALB PVALB CALML6 CALML6 UBA6 UBA6 ENSG00000167807 ENSG00000167807 CABP7 CABP7 EFCAB3 EFCAB3 MTRR MTRR CIAPIN1 CIAPIN1 EFCAB13 EFCAB13 CALM1 CALM1 FDX1L FDX1L FDX1 FDX1 CALM3 CALM3 CALM2 CALM2 RHBDL3 RHBDL3 CABP4 CABP4 EFCAB11 EFCAB11 SMS SMS CALML4 CALML4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
CABP7calcium binding protein 7; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity) (215 aa)
PVALBparvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (110 aa)
FDX1ferredoxin 1; Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (184 aa)
EFCAB6EF-hand calcium binding domain 6 (1501 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase; Involved in the reductive regeneration of cob(I)alamin cofactor required for the maintenance of methionine synthase in a functional state (725 aa)
RHBDL3rhomboid, veinlet-like 3 (Drosophila); May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors (By similarity) (404 aa)
CALM2calmodulin 2 (phosphorylase kinase, delta) (149 aa)
CALM3calmodulin 3 (phosphorylase kinase, delta) (149 aa)
MMADHCmethylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria; Involved in cobalamin metabolism (296 aa)
CALML6calmodulin-like 6 (181 aa)
UBA6ubiquitin-like modifier activating enzyme 6 (1052 aa)
CABP4calcium binding protein 4; Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages (By similarity) (275 aa)
EFCAB11EF-hand calcium binding domain 11 (163 aa)
EFCAB13EF-hand calcium binding domain 13 (973 aa)
SPATA21spermatogenesis associated 21; Involved in the differentiation of haploid spermatids (By similarity) (469 aa)
CALM1calmodulin 1 (phosphorylase kinase, delta) (149 aa)
EFCAB7EF-hand calcium binding domain 7 (629 aa)
SCGNsecretagogin, EF-hand calcium binding protein (276 aa)
CALML5calmodulin-like 5; Binds calcium. May be involved in terminal differentiation of keratinocytes (146 aa)
FDX1Lferredoxin 1-like; Essential for heme A and Fe/S protein biosynthesis (183 aa)
CIAPIN1cytokine induced apoptosis inhibitor 1; May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity) (312 aa)
MMACHCmethylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12) (282 aa)
SMSspermine synthase; Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM) (366 aa)
EFCAB3EF-hand calcium binding domain 3 (490 aa)
CALML4calmodulin-like 4 (196 aa)
ENSG00000167807Adrenodoxin-like protein, mitochondrial (145 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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