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P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins (535 aa) | |||
COL1A1 | collagen, type I, alpha 1 (1464 aa) | |||
ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2; Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis (1211 aa) | |||
GLT25D1 | glycosyltransferase 25 domain containing 1; Has a beta-galactosyltransferase activity; transfers beta-galactose to hydroxylysine residues of collagen (622 aa) | |||
COL5A3 | collagen, type V, alpha 3; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin (1745 aa) | |||
ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens (1205 aa) | |||
PCOLCE2 | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 (415 aa) | |||
PPIB | peptidylprolyl isomerase B (cyclophilin B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (216 aa) | |||
COL8A2 | collagen, type VIII, alpha 2; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity) (703 aa) | |||
COL19A1 | collagen, type XIX, alpha 1 (1142 aa) | |||
LEPREL1 | leprecan-like 1; Shows prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types II, IV and V (By similarity) (708 aa) | |||
CRTAP | cartilage associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues (401 aa) | |||
COL4A5 | collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1691 aa) | |||
P4HA3 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins (544 aa) | |||
COL7A1 | collagen, type VII, alpha 1; Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen (2944 aa) | |||
COL9A1 | collagen, type IX, alpha 1 (921 aa) | |||
COL6A6 | collagen, type VI, alpha 6; Collagen VI acts as a cell-binding protein (By similarity) (2263 aa) | |||
GLT25D2 | glycosyltransferase 25 domain containing 2; Has a beta-galactosyltransferase activity; transfers beta-galactose to hydroxylysine residues on collagen (626 aa) | |||
COL9A2 | collagen, type IX, alpha 2; Structural component of hyaline cartilage and vitreous of the eye (689 aa) | |||
ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity (1226 aa) | |||
COL5A2 | collagen, type V, alpha 2 (1499 aa) | |||
COL2A1 | collagen, type II, alpha 1 (1487 aa) | |||
COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) (1670 aa) | |||
COL4A4 | collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1690 aa) | |||
LEPREL2 | leprecan-like 2; Has prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V (By similarity) (735 aa) | |||
COL28A1 | collagen, type XXVIII, alpha 1; May act as a cell-binding protein (1125 aa) |