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DNAL4 | dynein, axonemal, light chain 4; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity) (105 aa) | |||
DCTN6 | dynactin 6 (190 aa) | |||
MAPRE3 | microtubule-associated protein, RP/EB family, member 3; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity) (281 aa) | |||
DNAH6 | dynein, axonemal, heavy chain 6 (4158 aa) | |||
DYNLL2 | dynein, light chain, LC8-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity) (89 aa) | |||
DNAI1 | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia (699 aa) | |||
DYNLL1 | dynein, light chain, LC8-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (89 aa) | |||
SNX4 | sorting nexin 4; May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation (450 aa) | |||
DNHD1 | dynein heavy chain domain 1 (4753 aa) | |||
DCTN3 | dynactin 3 (p22); Together with dynein may be involved in spindle assembly and cytokinesis (186 aa) | |||
KIF11 | kinesin family member 11; Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays (1056 aa) | |||
DNAH3 | dynein, axonemal, heavy chain 3 (4116 aa) | |||
DNAH9 | dynein, axonemal, heavy chain 9; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (4486 aa) | |||
DNAH5 | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles (4624 aa) | |||
WDR67 | WD repeat domain 67 (1066 aa) | |||
DNALI1 | dynein, axonemal, light intermediate chain 1; May play a dynamic role in flagellar motility (280 aa) | |||
MAPRE2 | microtubule-associated protein, RP/EB family, member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity) (327 aa) | |||
DNAH7 | dynein, axonemal, heavy chain 7 (4024 aa) | |||
CCDC114 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) (670 aa) | |||
DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and k [...] (645 aa) | |||
DNAH11 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (4523 aa) | |||
DNAH8 | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) (4695 aa) | |||
MAPRE1 | microtubule-associated protein, RP/EB family, member 1; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (268 aa) | |||
PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet- activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity). Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated [...] (410 aa) | |||
DNAH1 | dynein, axonemal, heavy chain 1 (4265 aa) | |||
DCTN2 | dynactin 2 (p50); Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (406 aa) |