13 items (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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	OSTM1	osteopetrosis associated transmembrane protein 1; Required for osteoclast and melanocyte maturation and function (By similarity) (334 aa)
	TIMP1	TIMP metallopeptidase inhibitor 1; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14 (207 aa)
	LAMP3	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity (416 aa)
	ABCA3	ATP-binding cassette, sub-family A (ABC1), member 3; Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol (1704 aa)
	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (798 aa)
	LCP1	lymphocyte cytosolic protein 1 (L-plastin); Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69 (627 aa)
	PLS1	plastin 1; Actin-bundling protein in the absence of calcium (629 aa)
	NISCH	nischarin (1504 aa)
	PLS3	plastin 3; Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia (630 aa)
	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...] (536 aa)
	SGTB	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity) (304 aa)
	FLOT2	flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function (428 aa)
	RAB9A	RAB9A, member RAS oncogene family; Involved in the transport of proteins between the endosomes and the trans Golgi network (201 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA3	LAMP3	ENSP00000301732	ENSP00000265598	ATP-binding cassette, sub-family A (ABC1), member 3; Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.701
FLOT2	LAMP3	ENSP00000378368	ENSP00000265598	flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.593
FLOT2	SRC	ENSP00000378368	ENSP00000350941	flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...]	0.626
ITGB1	LAMP3	ENSP00000303351	ENSP00000265598	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.598
ITGB1	SRC	ENSP00000303351	ENSP00000350941	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...]	0.940
ITGB1	TIMP1	ENSP00000303351	ENSP00000218388	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	TIMP metallopeptidase inhibitor 1; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14	0.838
LAMP3	ABCA3	ENSP00000265598	ENSP00000301732	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	ATP-binding cassette, sub-family A (ABC1), member 3; Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol	0.701
LAMP3	FLOT2	ENSP00000265598	ENSP00000378368	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function	0.593
LAMP3	ITGB1	ENSP00000265598	ENSP00000303351	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.598
LAMP3	NISCH	ENSP00000265598	ENSP00000339958	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	nischarin	0.567
LAMP3	RAB9A	ENSP00000265598	ENSP00000420127	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	RAB9A, member RAS oncogene family; Involved in the transport of proteins between the endosomes and the trans Golgi network	0.624
LAMP3	SRC	ENSP00000265598	ENSP00000350941	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...]	0.583
LAMP3	TIMP1	ENSP00000265598	ENSP00000218388	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	TIMP metallopeptidase inhibitor 1; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14	0.569
NISCH	LAMP3	ENSP00000339958	ENSP00000265598	nischarin	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.567
NISCH	RAB9A	ENSP00000339958	ENSP00000420127	nischarin	RAB9A, member RAS oncogene family; Involved in the transport of proteins between the endosomes and the trans Golgi network	0.572
RAB9A	LAMP3	ENSP00000420127	ENSP00000265598	RAB9A, member RAS oncogene family; Involved in the transport of proteins between the endosomes and the trans Golgi network	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.624
RAB9A	NISCH	ENSP00000420127	ENSP00000339958	RAB9A, member RAS oncogene family; Involved in the transport of proteins between the endosomes and the trans Golgi network	nischarin	0.572
SRC	FLOT2	ENSP00000350941	ENSP00000378368	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...]	flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function	0.626
SRC	ITGB1	ENSP00000350941	ENSP00000303351	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...]	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.940
SRC	LAMP3	ENSP00000350941	ENSP00000265598	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...]	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.583

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