arrestin 3, retinal (X-arrestin); May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins

myosin IIIA; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing

arrestin, beta 1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G- protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and re [...]

arrestin, beta 2

arrestin, beta 1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G- protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and re [...]

myosin IIIA; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing

arrestin, beta 2

arrestin, beta 1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G- protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and re [...]

arrestin, beta 2

myosin IIIA; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing

centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function

myosin IIIA; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing

centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family member E

centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family, member F

centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family, member I

centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family, member J

centrin, EF-hand protein, 3; Plays a fundamental role in microtubule-organizing center structure and function

myosin IIIA; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing

centrin, EF-hand protein, 3; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family member E

centrin, EF-hand protein, 3; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family, member F

centrin, EF-hand protein, 3; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family, member I

centrin, EF-hand protein, 3; Plays a fundamental role in microtubule-organizing center structure and function

POTE ankyrin domain family, member J

dihydropyrimidinase-like 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)

espin; Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells (By similarity)

dihydropyrimidinase-like 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)

leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity)

dihydropyrimidinase-like 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)

myosin IA; Involved in directing the movement of organelles along actin filaments (Potential)

dihydropyrimidinase-like 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)

myosin IC; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell’s (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of ve [...]

dihydropyrimidinase-like 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)

myosin IIIA; Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing