Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DTX3 | RNF141 | ENSP00000338050 | ENSP00000265981 | deltex homolog 3 (Drosophila); Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity | ring finger protein 141; May be involved in spermatogenesis | 0.461 |
RNF141 | DTX3 | ENSP00000265981 | ENSP00000338050 | ring finger protein 141; May be involved in spermatogenesis | deltex homolog 3 (Drosophila); Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity | 0.461 |
RNF141 | TRIM24 | ENSP00000265981 | ENSP00000340507 | ring finger protein 141; May be involved in spermatogenesis | tripartite motif containing 24; Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at ’Lys-4’ (H3K4me0) and acetylated at ’Lys-23’ (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. U [...] | 0.491 |
RNF141 | TRIM8 | ENSP00000265981 | ENSP00000302120 | ring finger protein 141; May be involved in spermatogenesis | tripartite motif containing 8; Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1 (By similarity) | 0.461 |
TRIM24 | RNF141 | ENSP00000340507 | ENSP00000265981 | tripartite motif containing 24; Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at ’Lys-4’ (H3K4me0) and acetylated at ’Lys-23’ (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. U [...] | ring finger protein 141; May be involved in spermatogenesis | 0.491 |
TRIM24 | TRIM8 | ENSP00000340507 | ENSP00000302120 | tripartite motif containing 24; Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at ’Lys-4’ (H3K4me0) and acetylated at ’Lys-23’ (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. U [...] | tripartite motif containing 8; Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1 (By similarity) | 0.607 |
TRIM8 | RNF141 | ENSP00000302120 | ENSP00000265981 | tripartite motif containing 8; Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1 (By similarity) | ring finger protein 141; May be involved in spermatogenesis | 0.461 |
TRIM8 | TRIM24 | ENSP00000302120 | ENSP00000340507 | tripartite motif containing 8; Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1 (By similarity) | tripartite motif containing 24; Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at ’Lys-4’ (H3K4me0) and acetylated at ’Lys-23’ (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. U [...] | 0.607 |