aldehyde dehydrogenase 4 family, member A1

glutamate decarboxylase 1 (brain, 67kDa); Catalyzes the production of GABA

aldehyde dehydrogenase 4 family, member A1

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Catalyzes the production of GABA

aldehyde dehydrogenase 4 family, member A1

glutaminase; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity

aldehyde dehydrogenase 4 family, member A1

glutamate dehydrogenase 1; May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity)

aldehyde dehydrogenase 4 family, member A1

glutamate dehydrogenase 2; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission

aldehyde dehydrogenase 4 family, member A1

glutamate-ammonia ligase; This enzyme has 2 functions- it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts

aldehyde dehydrogenase 4 family, member A1

L-2-hydroxyglutarate dehydrogenase

aldehyde dehydrogenase 4 family, member A1

ubiquitin C

DnaJ (Hsp40) homolog, subfamily C, member 10

endoplasmic reticulum protein 27

DnaJ (Hsp40) homolog, subfamily C, member 10

protein disulfide isomerase family A, member 3

DnaJ (Hsp40) homolog, subfamily C, member 10

protein disulfide isomerase family A, member 4

DnaJ (Hsp40) homolog, subfamily C, member 10

protein disulfide isomerase-like, testis expressed; Probable redox-inactive chaperone involved in spermatogenesis

DnaJ (Hsp40) homolog, subfamily C, member 10

thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates A [...]

DnaJ (Hsp40) homolog, subfamily C, member 10

thioredoxin domain containing 2 (spermatozoa); Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase

DnaJ (Hsp40) homolog, subfamily C, member 10

ubiquitin C

endoplasmic reticulum protein 27

DnaJ (Hsp40) homolog, subfamily C, member 10

endoplasmic reticulum protein 27

endoplasmic reticulum protein 44; Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum

endoplasmic reticulum protein 27

protein disulfide isomerase family A, member 3

endoplasmic reticulum protein 27

protein disulfide isomerase family A, member 4

endoplasmic reticulum protein 27

thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates A [...]