Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | RPS5 | ribosomal protein S5 (204 aa) | ||
 | RPL6 | ribosomal protein L6; Specifically binds to domain C of the Tax-responsive enhancer element in the long terminal repeat of HTLV-I (288 aa) | ||
 | SRP54 | signal recognition particle 54kDa; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein) (504 aa) | ||
 | RPN2 | ribophorin II; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (631 aa) | ||
 | RPS16 | ribosomal protein S16 (146 aa) | ||
 | RPL35 | ribosomal protein L35 (123 aa) | ||
 | RPL26L1 | ribosomal protein L26-like 1 (145 aa) | ||
 | SEC11A | SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) (179 aa) | ||
 | RPS11 | ribosomal protein S11 (158 aa) | ||
 | RPL37 | ribosomal protein L37; Binds to the 23S rRNA (By similarity) (97 aa) | ||
 | RPL30 | ribosomal protein L30 (115 aa) | ||
 | RPL26 | ribosomal protein L26 (145 aa) | ||
 | RPL29 | ribosomal protein L29 (159 aa) | ||
 | SSR2 | signal sequence receptor, beta (translocon-associated protein beta); TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins (183 aa) | ||
 | RPS23 | ribosomal protein S23 (143 aa) | ||
 | RPL38 | ribosomal protein L38 (70 aa) | ||
 | RPS14 | ribosomal protein S14 (151 aa) | ||
 | RPS15A | ribosomal protein S15a (130 aa) | ||
 | RPLP2 | ribosomal protein, large, P2; Plays an important role in the elongation step of protein synthesis (115 aa) | ||
 | SRPR | signal recognition particle receptor (docking protein); Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (638 aa) | ||
 | RPLP0 | ribosomal protein, large, P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10 (By similarity) (317 aa) | ||
 | RPS7 | ribosomal protein S7; Required for rRNA maturation (194 aa) | ||
 | RPL7 | ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (248 aa) | ||
 | SEC61G | Sec61 gamma subunit; Necessary for protein translocation in the endoplasmic reticulum (By similarity) (68 aa) | ||
 | RPS2 | ribosomal protein S2 (293 aa) | ||
 | UBC | ubiquitin C (685 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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