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STRINGSTRING
SECISBP2L SECISBP2L PSG3 PSG3 PSG9 PSG9 PSG1 PSG1 CELSR3 CELSR3 SHCBP1 SHCBP1 NEFM NEFM ATP6V1E1 ATP6V1E1 APOL2 APOL2 SMAD9 SMAD9 ZMYM1 ZMYM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
CELSR3cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation (3312 aa)
NEFMneurofilament, medium polypeptide; Neurofilaments usually contain three intermediate filament proteins- L, M, and H which are involved in the maintenance of neuronal caliber (916 aa)
PSG1pregnancy specific beta-1-glycoprotein 1 (426 aa)
APOL2apolipoprotein L, 2 (337 aa)
ATP6V1E1ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (226 aa)
PSG9pregnancy specific beta-1-glycoprotein 9 (426 aa)
SHCBP1SHC SH2-domain binding protein 1; May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells (By similarity) (672 aa)
PSG3pregnancy specific beta-1-glycoprotein 3 (428 aa)
ZMYM1zinc finger, MYM-type 1 (1142 aa)
SMAD9SMAD family member 9; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD) (467 aa)
SECISBP2LSECIS binding protein 2-like (1101 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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