Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | MRPS10 | mitochondrial ribosomal protein S10 (201 aa) | ||
 | MRPS35 | mitochondrial ribosomal protein S35 (323 aa) | ||
 | RPS5 | ribosomal protein S5 (204 aa) | ||
 | MRPS2 | mitochondrial ribosomal protein S2 (296 aa) | ||
 | MRPS7 | mitochondrial ribosomal protein S7 (242 aa) | ||
 | MRPS9 | mitochondrial ribosomal protein S9 (396 aa) | ||
 | RPS11 | ribosomal protein S11 (158 aa) | ||
 | MRPS5 | mitochondrial ribosomal protein S5 (430 aa) | ||
 | TMEM43 | transmembrane protein 43; May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane (By similarity) (400 aa) | ||
 | EEF2 | eukaryotic translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (858 aa) | ||
 | MRPS12 | mitochondrial ribosomal protein S12 (138 aa) | ||
 | RPS15A | ribosomal protein S15a (130 aa) | ||
 | TUFM | Tu translation elongation factor, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (455 aa) | ||
 | DAP3 | death associated protein 3; Involved in mediating interferon-gamma-induced cell death (398 aa) | ||
 | UBC | ubiquitin C (685 aa) | ||
 | RPS3A | ribosomal protein S3A; May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity) (264 aa) | ||
 | HIBCH | 3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa) | ||
 | GALNT2 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region (571 aa) | ||
 | ZMPSTE24 | zinc metallopeptidase STE24 homolog (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C (475 aa) | ||
 | MRPS16 | mitochondrial ribosomal protein S16 (137 aa) | ||
 | MRPS15 | mitochondrial ribosomal protein S15 (257 aa) | ||
 | RPS6 | ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (249 aa) | ||
 | METTL17 | methyltransferase like 17; May be a component of the mitochondrial small ribosomal subunit (By similarity) (478 aa) | ||
 | MRPS6 | mitochondrial ribosomal protein S6 (125 aa) | ||
 | UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 (128 aa) | ||
 | RPS24 | ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits (289 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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