node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SNAP23 | SNAP29 | ENSP00000249647 | ENSP00000215730 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | synaptosomal-associated protein, 29kDa; SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps | 0.731 |
SNAP23 | SNAP47 | ENSP00000249647 | ENSP00000355721 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | synaptosomal-associated protein, 47kDa | 0.711 |
SNAP23 | STX11 | ENSP00000249647 | ENSP00000356540 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network | 0.993 |
SNAP23 | STX19 | ENSP00000249647 | ENSP00000320679 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 19 | 0.740 |
SNAP23 | STX1A | ENSP00000249647 | ENSP00000222812 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 1A (brain) | 0.887 |
SNAP23 | STX1B | ENSP00000249647 | ENSP00000215095 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity) | 0.992 |
SNAP23 | STX2 | ENSP00000249647 | ENSP00000376178 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 2; Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm | 0.999 |
SNAP23 | STX3 | ENSP00000249647 | ENSP00000338562 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 3; Potentially involved in docking of synaptic vesicles at presynaptic active zones | 0.999 |
SNAP23 | STX4 | ENSP00000249647 | ENSP00000317714 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones | 0.999 |
SNAP23 | UBC | ENSP00000249647 | ENSP00000344818 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | ubiquitin C | 0.923 |
SNAP25 | SNAP29 | ENSP00000254976 | ENSP00000215730 | synaptosomal-associated protein, 25kDa | synaptosomal-associated protein, 29kDa; SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps | 0.941 |
SNAP25 | SNAP47 | ENSP00000254976 | ENSP00000355721 | synaptosomal-associated protein, 25kDa | synaptosomal-associated protein, 47kDa | 0.520 |
SNAP25 | STX11 | ENSP00000254976 | ENSP00000356540 | synaptosomal-associated protein, 25kDa | syntaxin 11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network | 0.867 |
SNAP25 | STX19 | ENSP00000254976 | ENSP00000320679 | synaptosomal-associated protein, 25kDa | syntaxin 19 | 0.692 |
SNAP25 | STX1A | ENSP00000254976 | ENSP00000222812 | synaptosomal-associated protein, 25kDa | syntaxin 1A (brain) | 0.929 |
SNAP25 | STX1B | ENSP00000254976 | ENSP00000215095 | synaptosomal-associated protein, 25kDa | syntaxin 1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity) | 0.982 |
SNAP25 | STX2 | ENSP00000254976 | ENSP00000376178 | synaptosomal-associated protein, 25kDa | syntaxin 2; Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm | 0.993 |
SNAP25 | STX3 | ENSP00000254976 | ENSP00000338562 | synaptosomal-associated protein, 25kDa | syntaxin 3; Potentially involved in docking of synaptic vesicles at presynaptic active zones | 0.996 |
SNAP25 | STX4 | ENSP00000254976 | ENSP00000317714 | synaptosomal-associated protein, 25kDa | syntaxin 4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones | 0.999 |
SNAP29 | SNAP23 | ENSP00000215730 | ENSP00000249647 | synaptosomal-associated protein, 29kDa; SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | 0.731 |