26 items (Homo sapiens) - STRING network view

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	ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma; Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP (225 aa)
	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (201 aa)
	SLC7A14	solute carrier family 7 (orphan transporter), member 14 (771 aa)
	ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2 (655 aa)
	ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (651 aa)
	CHTF18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae); Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single- stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18- RFC complex [...] (975 aa)
	SLC9A3R1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli ( [...] (358 aa)
	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity) (204 aa)
	ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (673 aa)
	SLC22A9	solute carrier family 22 (organic anion transporter), member 9 (553 aa)
	ABCG4	ATP-binding cassette, sub-family G (WHITE), member 4; May be involved in macrophage lipid homeostasis (646 aa)
	C7orf10	chromosome 7 open reading frame 10 (471 aa)
	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae); Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3 (393 aa)
	NR2C2AP	nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes (139 aa)
	PPOX	protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX (477 aa)
	PDZD3	PDZ domain containing 3; Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions (505 aa)
	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1 (678 aa)
	TSNAX	translin-associated factor X; Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (290 aa)
	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent); Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (749 aa)
	GPN2	GPN-loop GTPase 2 (310 aa)
	AMACR	alpha-methylacyl-CoA racemase (394 aa)
	ESYT3	extended synaptotagmin-like protein 3; May play a role as calcium-regulated intrinsic membrane protein (By similarity) (886 aa)
	DIAPH1	diaphanous homolog 1 (Drosophila); Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and pr [...] (1272 aa)
	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5; Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons (1139 aa)
	SLC12A4	solute carrier family 12 (potassium/chloride transporters), member 4 (1087 aa)
	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus (337 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG1	ABCG2	ENSP00000354995	ENSP00000237612	ATP-binding cassette, sub-family G (WHITE), member 1	ATP-binding cassette, sub-family G (WHITE), member 2	0.647
ABCG1	ABCG4	ENSP00000354995	ENSP00000304111	ATP-binding cassette, sub-family G (WHITE), member 1	ATP-binding cassette, sub-family G (WHITE), member 4; May be involved in macrophage lipid homeostasis	0.817
ABCG1	ABCG5	ENSP00000354995	ENSP00000260645	ATP-binding cassette, sub-family G (WHITE), member 1	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	0.699
ABCG2	ABCG1	ENSP00000237612	ENSP00000354995	ATP-binding cassette, sub-family G (WHITE), member 2	ATP-binding cassette, sub-family G (WHITE), member 1	0.647
ABCG2	ABCG4	ENSP00000237612	ENSP00000304111	ATP-binding cassette, sub-family G (WHITE), member 2	ATP-binding cassette, sub-family G (WHITE), member 4; May be involved in macrophage lipid homeostasis	0.644
ABCG2	ABCG5	ENSP00000237612	ENSP00000260645	ATP-binding cassette, sub-family G (WHITE), member 2	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	0.647
ABCG2	ABCG8	ENSP00000237612	ENSP00000272286	ATP-binding cassette, sub-family G (WHITE), member 2	ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	0.617
ABCG2	SLC22A9	ENSP00000237612	ENSP00000279178	ATP-binding cassette, sub-family G (WHITE), member 2	solute carrier family 22 (organic anion transporter), member 9	0.544
ABCG4	ABCG1	ENSP00000304111	ENSP00000354995	ATP-binding cassette, sub-family G (WHITE), member 4; May be involved in macrophage lipid homeostasis	ATP-binding cassette, sub-family G (WHITE), member 1	0.817
ABCG4	ABCG2	ENSP00000304111	ENSP00000237612	ATP-binding cassette, sub-family G (WHITE), member 4; May be involved in macrophage lipid homeostasis	ATP-binding cassette, sub-family G (WHITE), member 2	0.644
ABCG5	ABCG1	ENSP00000260645	ENSP00000354995	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	ATP-binding cassette, sub-family G (WHITE), member 1	0.699
ABCG5	ABCG2	ENSP00000260645	ENSP00000237612	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	ATP-binding cassette, sub-family G (WHITE), member 2	0.647
ABCG5	ABCG8	ENSP00000260645	ENSP00000272286	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	0.985
ABCG8	ABCG2	ENSP00000272286	ENSP00000237612	ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	ATP-binding cassette, sub-family G (WHITE), member 2	0.617
ABCG8	ABCG5	ENSP00000272286	ENSP00000260645	ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile	0.985
ARHGDIA	ARHGDIB	ENSP00000269321	ENSP00000228945	Rho GDP dissociation inhibitor (GDI) alpha; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity)	Rho GDP dissociation inhibitor (GDI) beta; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them	0.901
ARHGDIA	ARHGDIG	ENSP00000269321	ENSP00000219409	Rho GDP dissociation inhibitor (GDI) alpha; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity)	Rho GDP dissociation inhibitor (GDI) gamma; Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP	0.902
ARHGDIA	SLC9A3R1	ENSP00000269321	ENSP00000262613	Rho GDP dissociation inhibitor (GDI) alpha; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity)	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli ( [...]	0.407
ARHGDIB	ARHGDIA	ENSP00000228945	ENSP00000269321	Rho GDP dissociation inhibitor (GDI) beta; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them	Rho GDP dissociation inhibitor (GDI) alpha; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity)	0.901
ARHGDIB	ARHGDIG	ENSP00000228945	ENSP00000219409	Rho GDP dissociation inhibitor (GDI) beta; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them	Rho GDP dissociation inhibitor (GDI) gamma; Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP	0.903

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