node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABI1 | CDC123 | ENSP00000365312 | ENSP00000281141 | abl-interactor 1 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | 0.644 |
ABI1 | UBC | ENSP00000365312 | ENSP00000344818 | abl-interactor 1 | ubiquitin C | 0.620 |
ARFRP1 | CDC123 | ENSP00000326884 | ENSP00000281141 | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | 0.435 |
ARL13B | UBC | ENSP00000377769 | ENSP00000344818 | ADP-ribosylation factor-like 13B | ubiquitin C | 0.689 |
CDC123 | ABI1 | ENSP00000281141 | ENSP00000365312 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | abl-interactor 1 | 0.644 |
CDC123 | ARFRP1 | ENSP00000281141 | ENSP00000326884 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | 0.435 |
CDC123 | EIF2S3 | ENSP00000281141 | ENSP00000253039 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a re [...] | 0.843 |
CDC123 | EIF2S3L | ENSP00000281141 | ENSP00000445077 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | Putative eukaryotic translation initiation factor 2 subunit 3-like protein ; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by wa [...] | 0.830 |
CDC123 | SLMAP | ENSP00000281141 | ENSP00000295951 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | sarcolemma associated protein | 0.751 |
CDC123 | TPM3 | ENSP00000281141 | ENSP00000357516 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | tropomyosin 3; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments | 0.644 |
CDC123 | UBC | ENSP00000281141 | ENSP00000344818 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | ubiquitin C | 0.925 |
CDC123 | ZNF259 | ENSP00000281141 | ENSP00000227322 | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | zinc finger protein 259; May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus | 0.644 |
EIF2S3 | CDC123 | ENSP00000253039 | ENSP00000281141 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a re [...] | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | 0.843 |
EIF2S3 | EIF3I | ENSP00000253039 | ENSP00000362688 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a re [...] | eukaryotic translation initiation factor 3, subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination riboso [...] | 0.991 |
EIF2S3 | UBC | ENSP00000253039 | ENSP00000344818 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a re [...] | ubiquitin C | 0.986 |
EIF2S3L | CDC123 | ENSP00000445077 | ENSP00000281141 | Putative eukaryotic translation initiation factor 2 subunit 3-like protein ; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by wa [...] | cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) | 0.830 |
EIF2S3L | EIF3I | ENSP00000445077 | ENSP00000362688 | Putative eukaryotic translation initiation factor 2 subunit 3-like protein ; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by wa [...] | eukaryotic translation initiation factor 3, subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination riboso [...] | 0.980 |
EIF2S3L | UBC | ENSP00000445077 | ENSP00000344818 | Putative eukaryotic translation initiation factor 2 subunit 3-like protein ; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by wa [...] | ubiquitin C | 0.400 |
EIF3I | EIF2S3 | ENSP00000362688 | ENSP00000253039 | eukaryotic translation initiation factor 3, subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination riboso [...] | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a re [...] | 0.991 |
EIF3I | EIF2S3L | ENSP00000362688 | ENSP00000445077 | eukaryotic translation initiation factor 3, subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2-GTP-methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination riboso [...] | Putative eukaryotic translation initiation factor 2 subunit 3-like protein ; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by wa [...] | 0.980 |