node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MOGS | PIGG | ENSP00000233616 | ENSP00000415203 | mannosyl-oligosaccharide glucosidase; Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner | phosphatidylinositol glycan anchor biosynthesis, class G | 0.430 |
ORMDL1 | PIGO | ENSP00000326869 | ENSP00000339382 | ORM1-like 1 (S. cerevisiae); Negative regulator of sphingolipid synthesis | phosphatidylinositol glycan anchor biosynthesis, class O; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity) | 0.570 |
PIGB | PIGF | ENSP00000164305 | ENSP00000281382 | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | 0.971 |
PIGB | PIGG | ENSP00000164305 | ENSP00000415203 | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly | phosphatidylinositol glycan anchor biosynthesis, class G | 0.724 |
PIGB | PIGK | ENSP00000164305 | ENSP00000359848 | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly | phosphatidylinositol glycan anchor biosynthesis, class K; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein | 0.680 |
PIGB | PIGO | ENSP00000164305 | ENSP00000339382 | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly | phosphatidylinositol glycan anchor biosynthesis, class O; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity) | 0.969 |
PIGB | PIGU | ENSP00000164305 | ENSP00000217446 | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly | phosphatidylinositol glycan anchor biosynthesis, class U; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI | 0.407 |
PIGF | PIGB | ENSP00000281382 | ENSP00000164305 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly | 0.971 |
PIGF | PIGG | ENSP00000281382 | ENSP00000415203 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class G | 0.986 |
PIGF | PIGK | ENSP00000281382 | ENSP00000359848 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class K; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein | 0.923 |
PIGF | PIGO | ENSP00000281382 | ENSP00000339382 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class O; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity) | 0.986 |
PIGF | PIGS | ENSP00000281382 | ENSP00000309430 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class S; Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates | 0.906 |
PIGF | PIGT | ENSP00000281382 | ENSP00000279036 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class T | 0.917 |
PIGF | PIGU | ENSP00000281382 | ENSP00000217446 | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | phosphatidylinositol glycan anchor biosynthesis, class U; Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI | 0.926 |
PIGG | MOGS | ENSP00000415203 | ENSP00000233616 | phosphatidylinositol glycan anchor biosynthesis, class G | mannosyl-oligosaccharide glucosidase; Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner | 0.430 |
PIGG | PIGB | ENSP00000415203 | ENSP00000164305 | phosphatidylinositol glycan anchor biosynthesis, class G | phosphatidylinositol glycan anchor biosynthesis, class B; Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly | 0.724 |
PIGG | PIGF | ENSP00000415203 | ENSP00000281382 | phosphatidylinositol glycan anchor biosynthesis, class G | phosphatidylinositol glycan anchor biosynthesis, class F; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI (By similarity) | 0.986 |
PIGG | PIGK | ENSP00000415203 | ENSP00000359848 | phosphatidylinositol glycan anchor biosynthesis, class G | phosphatidylinositol glycan anchor biosynthesis, class K; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein | 0.872 |
PIGG | PIGO | ENSP00000415203 | ENSP00000339382 | phosphatidylinositol glycan anchor biosynthesis, class G | phosphatidylinositol glycan anchor biosynthesis, class O; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond (By similarity) | 0.951 |
PIGG | PIGT | ENSP00000415203 | ENSP00000279036 | phosphatidylinositol glycan anchor biosynthesis, class G | phosphatidylinositol glycan anchor biosynthesis, class T | 0.470 |