Your Input:
|
||||
RANBP9 | RAN binding protein 9; May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity o [...] (729 aa) | |||
YPEL5 | yippee-like 5 (Drosophila) (121 aa) | |||
GID8 | GID complex subunit 8 homolog (S. cerevisiae) (228 aa) | |||
RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) (391 aa) | |||
KBTBD5 | kelch repeat and BTB (POZ) domain containing 5 (621 aa) | |||
YPEL4 | yippee-like 4 (Drosophila) (127 aa) | |||
SPRYD3 | SPRY domain containing 3 (442 aa) | |||
MAEA | macrophage erythroblast attacher; Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events (396 aa) | |||
YPEL2 | yippee-like 2 (Drosophila) (119 aa) | |||
RANBP10 | RAN binding protein 10; Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos [...] (620 aa) | |||
MKLN1 | muskelin 1, intracellular mediator containing kelch motifs; Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1 (By similarity) (735 aa) | |||
SOX2 | SRY (sex determining region Y)-box 2; Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiat [...] (317 aa) | |||
YPEL1 | yippee-like 1 (Drosophila); May play a role in epithelioid conversion of fibroblasts (119 aa) | |||
C21orf2 | chromosome 21 open reading frame 2; May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization (256 aa) | |||
UBC | ubiquitin C (685 aa) | |||
KLHL31 | kelch-like 31 (Drosophila); Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (634 aa) | |||
VKORC1 | vitamin K epoxide reductase complex, subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K (163 aa) | |||
IPP | intracisternal A particle-promoted polypeptide; May play a role in organizing the actin cytoskeleton (584 aa) | |||
YPEL3 | yippee-like 3 (Drosophila); Involved in proliferation and apoptosis in myeloid precursor cells (By similarity) (157 aa) | |||
KBTBD8 | kelch repeat and BTB (POZ) domain containing 8 (601 aa) | |||
WDR26 | WD repeat domain 26; May be involved in MAPK pathways (661 aa) | |||
ARMC8 | armadillo repeat containing 8 (659 aa) | |||
KLHL2 | kelch-like 2, Mayven (Drosophila); Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors (597 aa) |