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ERBB3 ERBB3 RNF2 RNF2 UBC UBC RPS5 RPS5 RPS14 RPS14 RPS20 RPS20 MRPS18A MRPS18A RPS2 RPS2 RPSAP58 RPSAP58 MRPS12 MRPS12 RPSA RPSA MRPS2 MRPS2 MRPS18C MRPS18C MRPS9 MRPS9 MRPS5 MRPS5 ICT1 ICT1 MRPS10 MRPS10 MRPS15 MRPS15 MRPS14 MRPS14 MRPS16 MRPS16 MRPS11 MRPS11 MRPS7 MRPS7 MRPS6 MRPS6 MRPS24 MRPS24 MRPS17 MRPS17 MRPS21 MRPS21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
MRPS10mitochondrial ribosomal protein S10 (201 aa)
RPS5ribosomal protein S5 (204 aa)
MRPS2mitochondrial ribosomal protein S2 (296 aa)
MRPS7mitochondrial ribosomal protein S7 (242 aa)
MRPS9mitochondrial ribosomal protein S9 (396 aa)
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); Binds and is activated by neuregulins and NTAK (1342 aa)
MRPS5mitochondrial ribosomal protein S5 (430 aa)
MRPS17mitochondrial ribosomal protein S17 (130 aa)
MRPS18Cmitochondrial ribosomal protein S18C (142 aa)
ICT1immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (206 aa)
MRPS12mitochondrial ribosomal protein S12 (138 aa)
RPS14ribosomal protein S14 (151 aa)
MRPS21mitochondrial ribosomal protein S21 (87 aa)
MRPS11mitochondrial ribosomal protein S11 (194 aa)
MRPS24mitochondrial ribosomal protein S24 (167 aa)
RPS2ribosomal protein S2 (293 aa)
UBCubiquitin C (685 aa)
RPSAribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. A [...] (295 aa)
RPSAP58ribosomal protein SA pseudogene 58; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, a [...] (295 aa)
RNF2ring finger protein 2; E3 ubiquitin-protein ligase that mediates monoubiquitination of ’Lys-119’ of histone H2A, thereby playing a central role in histone code and gene regulation. H2A ’Lys-119’ ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, includ [...] (336 aa)
MRPS18Amitochondrial ribosomal protein S18A (196 aa)
MRPS16mitochondrial ribosomal protein S16 (137 aa)
MRPS15mitochondrial ribosomal protein S15 (257 aa)
MRPS6mitochondrial ribosomal protein S6 (125 aa)
MRPS14mitochondrial ribosomal protein S14 (128 aa)
RPS20ribosomal protein S20 (142 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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