node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAMTS3 | BMP1 | ENSP00000286657 | ENSP00000305714 | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | bone morphogenetic protein 1 | 0.923 |
ADAMTS3 | PCOLCE | ENSP00000286657 | ENSP00000223061 | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | 0.917 |
ADAMTS3 | PCOLCE2 | ENSP00000286657 | ENSP00000295992 | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | 0.904 |
ADAMTS3 | TLL1 | ENSP00000286657 | ENSP00000061240 | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | 0.902 |
BMP1 | ADAMTS3 | ENSP00000305714 | ENSP00000286657 | bone morphogenetic protein 1 | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | 0.923 |
BMP1 | PCOLCE | ENSP00000305714 | ENSP00000223061 | bone morphogenetic protein 1 | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | 0.922 |
BMP1 | PCOLCE2 | ENSP00000305714 | ENSP00000295992 | bone morphogenetic protein 1 | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | 0.921 |
BMP1 | TLL1 | ENSP00000305714 | ENSP00000061240 | bone morphogenetic protein 1 | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | 0.901 |
PCOLCE | ADAMTS3 | ENSP00000223061 | ENSP00000286657 | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | 0.917 |
PCOLCE | BMP1 | ENSP00000223061 | ENSP00000305714 | procollagen C-endopeptidase enhancer; Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity | bone morphogenetic protein 1 | 0.922 |
PCOLCE2 | ADAMTS3 | ENSP00000295992 | ENSP00000286657 | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | 0.904 |
PCOLCE2 | BMP1 | ENSP00000295992 | ENSP00000305714 | procollagen C-endopeptidase enhancer 2; Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 | bone morphogenetic protein 1 | 0.921 |
TLL1 | ADAMTS3 | ENSP00000061240 | ENSP00000286657 | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | ADAM metallopeptidase with thrombospondin type 1 motif, 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens | 0.902 |
TLL1 | BMP1 | ENSP00000061240 | ENSP00000305714 | tolloid-like 1; Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis | bone morphogenetic protein 1 | 0.901 |