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BTNL9 BTNL9 BTN3A3 BTN3A3 B4GALT5 B4GALT5 BTN1A1 BTN1A1 BTN2A1 BTN2A1 TAPBPL TAPBPL B4GALT6 B4GALT6 BTN2A2 BTN2A2 B4GALT3 B4GALT3 SIRPB1 SIRPB1 HSPG2 HSPG2 BTN3A1 BTN3A1 BAG3 BAG3 SIRPA SIRPA LYZL4 LYZL4 B4GALT4 B4GALT4 SIRPG SIRPG B4GALT2 B4GALT2 CD172b CD172b B4GALT1 B4GALT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
BTN1A1butyrophilin, subfamily 1, member A1; May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity) (526 aa)
BTN3A3butyrophilin, subfamily 3, member A3; Plays a role in T-cell responses in the adaptive immune response (584 aa)
TAPBPLTAP binding protein-like (468 aa)
SIRPB1signal-regulatory protein beta 1; Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK (398 aa)
LYZL4lysozyme-like 4 (146 aa)
BTN3A1butyrophilin, subfamily 3, member A1 (513 aa)
SIRPGsignal-regulatory protein gamma; Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T- cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation (387 aa)
B4GALT6UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; Required for the biosynthesis of glycosphingolipids (382 aa)
B4GALT2UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 (401 aa)
BTN2A1butyrophilin, subfamily 2, member A1 (527 aa)
B4GALT3UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids (393 aa)
BTNL9butyrophilin-like 9 (535 aa)
SIRPAsignal-regulatory protein alpha (504 aa)
BTN2A2butyrophilin, subfamily 2, member A2; Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity) (523 aa)
B4GALT4UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids (344 aa)
BAG3BCL2-associated athanogene 3; Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity (575 aa)
B4GALT5UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids (388 aa)
HSPG2heparan sulfate proteoglycan 2; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development (4391 aa)
B4GALT1UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (398 aa)
CD172bUncharacterized protein ; Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK (177 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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