| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTBP1 | CTBP2 | ENSP00000290921 | ENSP00000311825 | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | 0.921 |
| CTBP1 | PSAT1 | ENSP00000290921 | ENSP00000365773 | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | phosphoserine aminotransferase 1; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) | 0.771 |
| CTBP1 | PSPH | ENSP00000290921 | ENSP00000275605 | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates | 0.404 |
| CTBP1 | UBC | ENSP00000290921 | ENSP00000344818 | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | ubiquitin C | 0.981 |
| CTBP2 | CTBP1 | ENSP00000311825 | ENSP00000290921 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity | 0.921 |
| CTBP2 | PSAT1 | ENSP00000311825 | ENSP00000365773 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | phosphoserine aminotransferase 1; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) | 0.771 |
| CTBP2 | PSPH | ENSP00000311825 | ENSP00000275605 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates | 0.404 |
| CTBP2 | UBC | ENSP00000311825 | ENSP00000344818 | C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) | ubiquitin C | 0.980 |
| GCSH | PDPR | ENSP00000319531 | ENSP00000288050 | glycine cleavage system protein H (aminomethyl carrier); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | pyruvate dehydrogenase phosphatase regulatory subunit; Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity) | 0.993 |
| GCSH | SHMT1 | ENSP00000319531 | ENSP00000318868 | glycine cleavage system protein H (aminomethyl carrier); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | serine hydroxymethyltransferase 1 (soluble); Interconversion of serine and glycine (By similarity) | 0.972 |
| GCSH | SHMT2 | ENSP00000319531 | ENSP00000333667 | glycine cleavage system protein H (aminomethyl carrier); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | serine hydroxymethyltransferase 2 (mitochondrial); Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA | 0.974 |
| PDPR | GCSH | ENSP00000288050 | ENSP00000319531 | pyruvate dehydrogenase phosphatase regulatory subunit; Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity) | glycine cleavage system protein H (aminomethyl carrier); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | 0.993 |
| PDPR | SHMT1 | ENSP00000288050 | ENSP00000318868 | pyruvate dehydrogenase phosphatase regulatory subunit; Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity) | serine hydroxymethyltransferase 1 (soluble); Interconversion of serine and glycine (By similarity) | 0.717 |
| PDPR | SHMT2 | ENSP00000288050 | ENSP00000333667 | pyruvate dehydrogenase phosphatase regulatory subunit; Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity) | serine hydroxymethyltransferase 2 (mitochondrial); Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA | 0.717 |
| PDPR | UBC | ENSP00000288050 | ENSP00000344818 | pyruvate dehydrogenase phosphatase regulatory subunit; Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine (By similarity) | ubiquitin C | 0.721 |
| PHGDH | PSAT1 | ENSP00000358417 | ENSP00000365773 | phosphoglycerate dehydrogenase | phosphoserine aminotransferase 1; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) | 0.996 |
| PHGDH | PSPH | ENSP00000358417 | ENSP00000275605 | phosphoglycerate dehydrogenase | phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates | 0.823 |
| PHGDH | SHMT1 | ENSP00000358417 | ENSP00000318868 | phosphoglycerate dehydrogenase | serine hydroxymethyltransferase 1 (soluble); Interconversion of serine and glycine (By similarity) | 0.590 |
| PHGDH | SHMT2 | ENSP00000358417 | ENSP00000333667 | phosphoglycerate dehydrogenase | serine hydroxymethyltransferase 2 (mitochondrial); Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA | 0.612 |
| PHGDH | UBC | ENSP00000358417 | ENSP00000344818 | phosphoglycerate dehydrogenase | ubiquitin C | 0.994 |
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