node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAZAP2 | IL17RB | ENSP00000448051 | ENSP00000288167 | DAZ associated protein 2 | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | 0.587 |
IL17B | IL17RB | ENSP00000261796 | ENSP00000288167 | interleukin 17B; Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1 | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | 0.982 |
IL17B | IL25 | ENSP00000261796 | ENSP00000328111 | interleukin 17B; Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1 | interleukin 25; Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses | 0.662 |
IL17RB | DAZAP2 | ENSP00000288167 | ENSP00000448051 | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | DAZ associated protein 2 | 0.587 |
IL17RB | IL17B | ENSP00000288167 | ENSP00000261796 | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | interleukin 17B; Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1 | 0.982 |
IL17RB | IL25 | ENSP00000288167 | ENSP00000328111 | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | interleukin 25; Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses | 0.992 |
IL17RB | TRAF6 | ENSP00000288167 | ENSP00000337853 | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | 0.585 |
IL25 | IL17B | ENSP00000328111 | ENSP00000261796 | interleukin 25; Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses | interleukin 17B; Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1 | 0.662 |
IL25 | IL17RB | ENSP00000328111 | ENSP00000288167 | interleukin 25; Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | 0.992 |
IL25 | TRAF3IP2 | ENSP00000328111 | ENSP00000357750 | interleukin 25; Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses | TRAF3 interacting protein 2 | 0.877 |
TRAF3IP2 | IL25 | ENSP00000357750 | ENSP00000328111 | TRAF3 interacting protein 2 | interleukin 25; Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses | 0.877 |
TRAF3IP2 | TRAF6 | ENSP00000357750 | ENSP00000337853 | TRAF3 interacting protein 2 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | 0.997 |
TRAF6 | IL17RB | ENSP00000337853 | ENSP00000288167 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | interleukin 17 receptor B; Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells | 0.585 |
TRAF6 | TRAF3IP2 | ENSP00000337853 | ENSP00000357750 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | TRAF3 interacting protein 2 | 0.997 |