node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHD1L | RBBP4 | ENSP00000358262 | ENSP00000362592 | chromodomain helicase DNA binding protein 1-like | retinoblastoma binding protein 4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome [...] | 0.625 |
CHD1L | RBBP7 | ENSP00000358262 | ENSP00000369424 | chromodomain helicase DNA binding protein 1-like | retinoblastoma binding protein 7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling [...] | 0.625 |
CHD1L | WDR59 | ENSP00000358262 | ENSP00000262144 | chromodomain helicase DNA binding protein 1-like | WD repeat domain 59 | 0.625 |
CHD1L | WDR73 | ENSP00000358262 | ENSP00000387982 | chromodomain helicase DNA binding protein 1-like | WD repeat domain 73 | 0.625 |
CSNK1A1 | ZNF618 | ENSP00000421689 | ENSP00000288466 | casein kinase 1, alpha 1 | zinc finger protein 618; May be involved in transcriptional regulation | 0.515 |
MLF1 | ZNF618 | ENSP00000376568 | ENSP00000288466 | myeloid leukemia factor 1; Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus | zinc finger protein 618; May be involved in transcriptional regulation | 0.693 |
MLF2 | ZNF618 | ENSP00000203630 | ENSP00000288466 | myeloid leukemia factor 2 | zinc finger protein 618; May be involved in transcriptional regulation | 0.693 |
RBBP4 | CHD1L | ENSP00000362592 | ENSP00000358262 | retinoblastoma binding protein 4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome [...] | chromodomain helicase DNA binding protein 1-like | 0.625 |
RBBP4 | RBBP7 | ENSP00000362592 | ENSP00000369424 | retinoblastoma binding protein 4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome [...] | retinoblastoma binding protein 7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling [...] | 0.999 |
RBBP7 | CHD1L | ENSP00000369424 | ENSP00000358262 | retinoblastoma binding protein 7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling [...] | chromodomain helicase DNA binding protein 1-like | 0.625 |
RBBP7 | RBBP4 | ENSP00000369424 | ENSP00000362592 | retinoblastoma binding protein 7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling [...] | retinoblastoma binding protein 4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome [...] | 0.999 |
WDR59 | CHD1L | ENSP00000262144 | ENSP00000358262 | WD repeat domain 59 | chromodomain helicase DNA binding protein 1-like | 0.625 |
WDR73 | CHD1L | ENSP00000387982 | ENSP00000358262 | WD repeat domain 73 | chromodomain helicase DNA binding protein 1-like | 0.625 |
ZNF618 | CSNK1A1 | ENSP00000288466 | ENSP00000421689 | zinc finger protein 618; May be involved in transcriptional regulation | casein kinase 1, alpha 1 | 0.515 |
ZNF618 | MLF1 | ENSP00000288466 | ENSP00000376568 | zinc finger protein 618; May be involved in transcriptional regulation | myeloid leukemia factor 1; Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus | 0.693 |
ZNF618 | MLF2 | ENSP00000288466 | ENSP00000203630 | zinc finger protein 618; May be involved in transcriptional regulation | myeloid leukemia factor 2 | 0.693 |