adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

adenosine A1 receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

complement component 5; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

chemokine (C-C motif) receptor 2; Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

chemokine (C-C motif) receptor 3; Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

chemokine (C-X-C motif) ligand 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

chemokine (C-X-C motif) receptor 7; Receptor for chemokines CXCL12/SDF1 and CXCL11. Does not elicit classical chemokine receptor signaling; chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Acts as a scavenger for CXCL12/SDF1 and, to a lesser extent, for CXCL11. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, [...]

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

galanin receptor 1; Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

G protein-coupled receptor 18; Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

interleukin 8

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

neuromedin U receptor 2; Receptor for the neuromedin-U and neuromedin-S neuropeptides (By similarity)

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

opioid receptor, delta 1; Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

prodynorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity)

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

pro-melanin-concentrating hormone; MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

prostaglandin D2 receptor 2; Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

serum amyloid A1; Major acute phase reactant. Apolipoprotein of the HDL complex (By similarity)

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

somatostatin receptor 4; Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells

adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase

somatostatin receptor 5; Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase