Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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 | SRP54 | signal recognition particle 54kDa; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein) (504 aa) | ||
 | MRPL32 | mitochondrial ribosomal protein L32 (188 aa) | ||
 | MRPL27 | mitochondrial ribosomal protein L27 (148 aa) | ||
 | MRPL34 | mitochondrial ribosomal protein L34 (92 aa) | ||
 | MRPL4 | mitochondrial ribosomal protein L4 (311 aa) | ||
 | RPL35 | ribosomal protein L35 (123 aa) | ||
 | MRPL15 | mitochondrial ribosomal protein L15 (296 aa) | ||
 | MRPL17 | mitochondrial ribosomal protein L17 (175 aa) | ||
 | MRPL33 | mitochondrial ribosomal protein L33 (65 aa) | ||
 | MRPL16 | mitochondrial ribosomal protein L16; Component of the large subunit of mitochondrial ribosome (251 aa) | ||
 | MRPL11 | mitochondrial ribosomal protein L11 (192 aa) | ||
 | MRPL46 | mitochondrial ribosomal protein L46 (279 aa) | ||
 | MRPL12 | mitochondrial ribosomal protein L12 (198 aa) | ||
 | MRPL20 | mitochondrial ribosomal protein L20 (149 aa) | ||
 | RPL27A | ribosomal protein L27a (148 aa) | ||
 | RPL9 | ribosomal protein L9 (192 aa) | ||
 | MRPL24 | mitochondrial ribosomal protein L24 (216 aa) | ||
 | RPL5 | ribosomal protein L5; Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA (297 aa) | ||
 | RPL11 | ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) (178 aa) | ||
 | MRTO4 | mRNA turnover 4 homolog (S. cerevisiae); Involved in mRNA turnover and ribosome assembly (By similarity) (239 aa) | ||
 | MRPL36 | mitochondrial ribosomal protein L36; Component of the large subunit of the mitochondrial ribosome (Potential) (103 aa) | ||
 | MRPL2 | mitochondrial ribosomal protein L2 (305 aa) | ||
 | MRPL19 | mitochondrial ribosomal protein L19 (292 aa) | ||
 | RPL23 | ribosomal protein L23 (140 aa) | ||
 | RPL23A | ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA (By similarity) (156 aa) | ||
 | MRPL22 | mitochondrial ribosomal protein L22 (206 aa) | ||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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