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STRINGSTRING
STX16 STX16 LAPTM4B LAPTM4B ENSG00000254995 ENSG00000254995 BRI3 BRI3 SGK1 SGK1 SPRY3 SPRY3 SPRY2 SPRY2 LAPTM4A LAPTM4A FMNL2 FMNL2 TMEM184C TMEM184C FMNL3 FMNL3 FMNL1 FMNL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
LAPTM4Alysosomal protein transmembrane 4 alpha; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment (By similarity) (233 aa)
FMNL2formin-like 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics (1092 aa)
TMEM184Ctransmembrane protein 184C; Possible tumor suppressor which may play a role in cell growth (438 aa)
BRI3brain protein I3 (125 aa)
SPRY3sprouty homolog 3 (Drosophila); May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis (288 aa)
FMNL1formin-like 1; May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape (1100 aa)
FMNL3formin-like 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration (1027 aa)
SGK1serum/glucocorticoid regulated kinase 1 (526 aa)
STX16syntaxin 16 (325 aa)
SPRY2sprouty homolog 2 (Drosophila); May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis (315 aa)
LAPTM4Blysosomal protein transmembrane 4 beta (317 aa)
ENSG00000254995STX16-NPEPL1 readthrough (non-protein coding) (382 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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