node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATAD2B | UBB | ENSP00000238789 | ENSP00000304697 | ATPase family, AAA domain containing 2B | ubiquitin B | 0.430 |
ATAD2B | UBC | ENSP00000238789 | ENSP00000344818 | ATPase family, AAA domain containing 2B | ubiquitin C | 0.581 |
DDX10 | DKC1 | ENSP00000314348 | ENSP00000358563 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; Putative ATP-dependent RNA helicase | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | 0.768 |
DDX10 | NOP56 | ENSP00000314348 | ENSP00000370589 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; Putative ATP-dependent RNA helicase | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis | 0.842 |
DDX10 | RPL11 | ENSP00000314348 | ENSP00000363676 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; Putative ATP-dependent RNA helicase | ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) | 0.442 |
DDX10 | TRUB1 | ENSP00000314348 | ENSP00000298746 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; Putative ATP-dependent RNA helicase | TruB pseudouridine (psi) synthase homolog 1 (E. coli); May be responsible for synthesis of pseudouridine from uracil in transfer RNAs (By similarity) | 0.546 |
DDX10 | UBC | ENSP00000314348 | ENSP00000344818 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; Putative ATP-dependent RNA helicase | ubiquitin C | 0.803 |
DDX18 | DKC1 | ENSP00000263239 | ENSP00000358563 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; Probable RNA-dependent helicase | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | 0.778 |
DDX18 | NOP56 | ENSP00000263239 | ENSP00000370589 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; Probable RNA-dependent helicase | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis | 0.858 |
DDX18 | RPL11 | ENSP00000263239 | ENSP00000363676 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; Probable RNA-dependent helicase | ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) | 0.466 |
DDX18 | TRUB1 | ENSP00000263239 | ENSP00000298746 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; Probable RNA-dependent helicase | TruB pseudouridine (psi) synthase homolog 1 (E. coli); May be responsible for synthesis of pseudouridine from uracil in transfer RNAs (By similarity) | 0.546 |
DDX18 | UBC | ENSP00000263239 | ENSP00000344818 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; Probable RNA-dependent helicase | ubiquitin C | 0.944 |
DKC1 | DDX10 | ENSP00000358563 | ENSP00000314348 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; Putative ATP-dependent RNA helicase | 0.768 |
DKC1 | DDX18 | ENSP00000358563 | ENSP00000263239 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; Probable RNA-dependent helicase | 0.778 |
DKC1 | MRPL2 | ENSP00000358563 | ENSP00000373404 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | mitochondrial ribosomal protein L2 | 0.479 |
DKC1 | NEMF | ENSP00000358563 | ENSP00000298310 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | nuclear export mediator factor | 0.725 |
DKC1 | NOP56 | ENSP00000358563 | ENSP00000370589 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis | 0.997 |
DKC1 | PRPF4 | ENSP00000358563 | ENSP00000363313 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | PRP4 pre-mRNA processing factor 4 homolog (yeast); Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome | 0.406 |
DKC1 | RPL11 | ENSP00000358563 | ENSP00000363676 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) | 0.571 |
DKC1 | RPL8 | ENSP00000358563 | ENSP00000262584 | dyskeratosis congenita 1, dyskerin; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomera [...] | ribosomal protein L8 | 0.479 |