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STRINGSTRING
EGFR EGFR UBC UBC SCFD1 SCFD1 COG8 COG8 COG5 COG5 COG2 COG2 COG4 COG4 COG1 COG1 GOLGA3 GOLGA3 COG3 COG3 COG7 COG7 ENSG00000261576 ENSG00000261576 COG6 COG6 ENSG00000260371 ENSG00000260371
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
GOLGA3golgin A3; Golgi auto-antigen; probably involved in maintaining Golgi structure (1498 aa)
COG3component of oligomeric golgi complex 3; Involved in ER-Golgi transport (828 aa)
EGFRepidermal growth factor receptor (1210 aa)
COG5component of oligomeric golgi complex 5; Required for normal Golgi function (By similarity) (860 aa)
COG1component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) (980 aa)
COG7component of oligomeric golgi complex 7; Required for normal Golgi function (By similarity) (770 aa)
COG8component of oligomeric golgi complex 8; Required for normal Golgi function (By similarity) (612 aa)
COG4component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 (789 aa)
UBCubiquitin C (685 aa)
COG2component of oligomeric golgi complex 2; Required for normal Golgi morphology and function (738 aa)
SCFD1sec1 family domain containing 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity) (642 aa)
COG6component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) (657 aa)
ENSG00000260371Uncharacterized protein (156 aa)
ENSG00000261576Uncharacterized protein (164 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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