node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHSA1 | EEF1G | ENSP00000216479 | ENSP00000331901 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | 0.522 |
AHSA1 | ENSG00000232856 | ENSP00000216479 | ENSP00000403936 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking | hsa-mir-3654 | 0.501 |
AHSA1 | GCN1L1 | ENSP00000216479 | ENSP00000300648 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 0.669 |
AHSA1 | UBC | ENSP00000216479 | ENSP00000344818 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking | ubiquitin C | 0.858 |
AHSA2 | EEF1G | ENSP00000349525 | ENSP00000331901 | AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast); Co-chaperone that stimulates HSP90 ATPase activity (By similarity) | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | 0.501 |
AHSA2 | ENSG00000232856 | ENSP00000349525 | ENSP00000403936 | AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast); Co-chaperone that stimulates HSP90 ATPase activity (By similarity) | hsa-mir-3654 | 0.501 |
AHSA2 | GCN1L1 | ENSP00000349525 | ENSP00000300648 | AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast); Co-chaperone that stimulates HSP90 ATPase activity (By similarity) | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 0.669 |
CCT4 | EEF1G | ENSP00000377958 | ENSP00000331901 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | 0.483 |
CCT4 | ENSG00000232856 | ENSP00000377958 | ENSP00000403936 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | hsa-mir-3654 | 0.477 |
CCT4 | GCN1L1 | ENSP00000377958 | ENSP00000300648 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 0.877 |
CCT4 | ILK | ENSP00000377958 | ENSP00000299421 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | integrin-linked kinase; Receptor-proximal protein kinase regulating integrin- mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B | 0.785 |
CCT4 | ME1 | ENSP00000377958 | ENSP00000358719 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.707 |
CCT4 | ME2 | ENSP00000377958 | ENSP00000321070 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.707 |
CCT4 | ME3 | ENSP00000377958 | ENSP00000352657 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.707 |
CCT4 | OLA1 | ENSP00000377958 | ENSP00000284719 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | Obg-like ATPase 1 | 0.471 |
CCT4 | UBB | ENSP00000377958 | ENSP00000304697 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | ubiquitin B | 0.465 |
CCT4 | UBC | ENSP00000377958 | ENSP00000344818 | chaperonin containing TCP1, subunit 4 (delta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | ubiquitin C | 0.998 |
CDC5L | GCN1L1 | ENSP00000360532 | ENSP00000300648 | CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 0.737 |
CDC5L | UBC | ENSP00000360532 | ENSP00000344818 | CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing | ubiquitin C | 0.740 |
CLN3 | GCN1L1 | ENSP00000353073 | ENSP00000300648 | ceroid-lipofuscinosis, neuronal 3 | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 0.783 |