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CEP41 | centrosomal protein 41kDa (373 aa) | |||
CNTRL | centriolin (2325 aa) | |||
HAUS3 | HAUS augmin-like complex, subunit 3; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex (603 aa) | |||
HAUS2 | HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex (235 aa) | |||
OPTN | optineurin (577 aa) | |||
CEP70 | centrosomal protein 70kDa (597 aa) | |||
TCTN3 | tectonic family member 3 (607 aa) | |||
SCLT1 | sodium channel and clathrin linker 1; Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity) (688 aa) | |||
TUBA1A | tubulin, alpha 1a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) (451 aa) | |||
TCTN2 | tectonic family member 2; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity) (697 aa) | |||
CEP89 | centrosomal protein 89kDa (783 aa) | |||
FBF1 | Fas (TNFRSF6) binding factor 1; Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3 (1133 aa) | |||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis (589 aa) | |||
PCM1 | pericentriolar material 1; Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome. Involved in the biogenesis of cilia (2024 aa) | |||
TUBB | tubulin, beta class I (444 aa) | |||
TUBB4B | tubulin, beta 4B class IVb; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) (445 aa) | |||
FGFR1OP | FGFR1 oncogene partner; Required for anchoring microtubules to the centrosomes (399 aa) | |||
NPHP4 | nephronophthisis 4; Involved in the organization of apical junctions in kidney cells together with NPHP1 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity) (1426 aa) | |||
TUBB2A | tubulin, beta 2A class IIa; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) (445 aa) | |||
TUBAL3 | tubulin, alpha-like 3 (446 aa) | |||
HAUS6 | HAUS augmin-like complex, subunit 6 (955 aa) | |||
KIAA1009 | KIAA1009; Functions in cell division regulating chromosome segregation and mitotic spindle assembly (1403 aa) | |||
CC2D2A | coiled-coil and C2 domain containing 2A; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) (1620 aa) | |||
CEP192 | centrosomal protein 192kDa; Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication (2537 aa) | |||
RAB3IP | RAB3A interacting protein (rabin3) (476 aa) | |||
TUBB3 | tubulin, beta 3 class III; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) (797 aa) |