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MRPL52 MRPL52 MRPL38 MRPL38 MRPL39 MRPL39 LTV1 LTV1 NOB1 NOB1 MRPL37 MRPL37 MRPL50 MRPL50 TFB2M TFB2M DIMT1 DIMT1 TMEM177 TMEM177 TSR1 TSR1 BYSL BYSL MRPL40 MRPL40 RRP12 RRP12 RIOK2 RIOK2 MRPL32 MRPL32 MRPL44 MRPL44 UBC UBC PNO1 PNO1 MRPL47 MRPL47 RPS13 RPS13 MRPL19 MRPL19 MRPL24 MRPL24 EIF2A EIF2A RPS24 RPS24 RPS4X RPS4X
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
DIMT1DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3’-end of 18S rRNA in the 40S particle (By similarity) (313 aa)
MRPL32mitochondrial ribosomal protein L32 (188 aa)
BYSLbystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa)
MRPL44mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome (332 aa)
PNO1partner of NOB1 homolog (S. cerevisiae) (252 aa)
NOB1NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); May play a role in mRNA degradation (412 aa)
TMEM177transmembrane protein 177 (311 aa)
RIOK2RIO kinase 2 (yeast) (552 aa)
TSR1TSR1, 20S rRNA accumulation, homolog (S. cerevisiae); Required during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (804 aa)
MRPL39mitochondrial ribosomal protein L39 (353 aa)
MRPL38mitochondrial ribosomal protein L38 (380 aa)
MRPL40mitochondrial ribosomal protein L40 (206 aa)
UBCubiquitin C (685 aa)
MRPL52mitochondrial ribosomal protein L52 (123 aa)
MRPL37mitochondrial ribosomal protein L37 (423 aa)
MRPL24mitochondrial ribosomal protein L24 (216 aa)
TFB2Mtranscription factor B2, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity (396 aa)
LTV1LTV1 homolog (S. cerevisiae) (475 aa)
RRP12ribosomal RNA processing 12 homolog (S. cerevisiae) (1297 aa)
RPS4Xribosomal protein S4, X-linked (263 aa)
MRPL50mitochondrial ribosomal protein L50 (158 aa)
MRPL19mitochondrial ribosomal protein L19 (292 aa)
RPS24ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits (289 aa)
EIF2Aeukaryotic translation initiation factor 2A, 65kDa; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (585 aa)
MRPL47mitochondrial ribosomal protein L47 (250 aa)
RPS13ribosomal protein S13 (151 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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