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UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (556 aa) | |||
KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast); Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity) (381 aa) | |||
RPL36 | ribosomal protein L36 (105 aa) | |||
RPL35 | ribosomal protein L35 (123 aa) | |||
RPL8 | ribosomal protein L8 (257 aa) | |||
AKT1 | v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...] (480 aa) | |||
PELP1 | proline, glutamate and leucine rich protein 1; Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence- specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1. May have important functional implications in ER/growth [...] (1274 aa) | |||
RPS14 | ribosomal protein S14 (151 aa) | |||
DHX37 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 (1157 aa) | |||
RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) (280 aa) | |||
NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) (516 aa) | |||
FCF1 | FCF1 small subunit (SSU) processome component homolog (S. cerevisiae); Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly (By similarity) (198 aa) | |||
RPL36AL | ribosomal protein L36a-like (106 aa) | |||
RPL9 | ribosomal protein L9 (192 aa) | |||
RPLP1 | ribosomal protein, large, P1; Plays an important role in the elongation step of protein synthesis (114 aa) | |||
RPL22L1 | ribosomal protein L22-like 1 (122 aa) | |||
RPL22 | ribosomal protein L22 (128 aa) | |||
PDCD11 | programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA (1871 aa) | |||
NOP56 | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis (594 aa) | |||
RPL23 | ribosomal protein L23 (140 aa) | |||
RPL34 | ribosomal protein L34 (117 aa) | |||
RPL32 | ribosomal protein L32 (135 aa) | |||
EXOSC6 | exosome component 6; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] (272 aa) | |||
RPL28 | ribosomal protein L28 (169 aa) | |||
RPL41 | ribosomal protein L41 (25 aa) | |||
MLL | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) (3972 aa) |