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STRINGSTRING
SURF1 SURF1 SLC25A5 SLC25A5 GTP GTP SLC25A23 SLC25A23 ELAVL1 ELAVL1 SLC25A18 SLC25A18 SLC25A31 SLC25A31 TARDBP TARDBP MTG1 MTG1 SLC25A4 SLC25A4 UBC UBC SLC25A6 SLC25A6 SLC25A22 SLC25A22 APPBP2 APPBP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
APPBP2amyloid beta precursor protein (cytoplasmic tail) binding protein 2; May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface (585 aa)
TARDBPTAR DNA binding protein (414 aa)
SLC25A31solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility (315 aa)
SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane (298 aa)
SLC25A23solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (468 aa)
SLC25A22solute carrier family 25 (mitochondrial carrier- glutamate), member 22 (323 aa)
GTPMitochondrial GTPase 1 ; Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) (334 aa)
SLC25A18solute carrier family 25 (glutamate carrier), member 18; Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+) (315 aa)
UBCubiquitin C (685 aa)
SLC25A5solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (298 aa)
SURF1surfeit 1; Probably involved in the biogenesis of the COX complex (300 aa)
SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (298 aa)
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro (326 aa)
MTG1mitochondrial GTPase 1 homolog (S. cerevisiae); Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) (339 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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