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MRPL39 MRPL39 MRPL10 MRPL10 MRPL4 MRPL4 MRPS28 MRPS28 MRPL13 MRPL13 RPS15 RPS15 MRPS6 MRPS6 MRPL12 MRPL12 MRPS18C MRPS18C TP53I3 TP53I3 RPS11 RPS11 MRPL42 MRPL42 MRPS16 MRPS16 MRPL3 MRPL3 MRPL52 MRPL52 MRPS7 MRPS7 ICT1 ICT1 MRPS18A MRPS18A MRPL55 MRPL55 DDX28 DDX28 DAP3 DAP3 MRPL23 MRPL23 MRPL51 MRPL51 MTHFD1 MTHFD1 UQCRFS1 UQCRFS1 CALU CALU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
MRPL51mitochondrial ribosomal protein L51 (128 aa)
TP53I3tumor protein p53 inducible protein 3; May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro) (332 aa)
MRPS7mitochondrial ribosomal protein S7 (242 aa)
MRPL4mitochondrial ribosomal protein L4 (311 aa)
MRPL3mitochondrial ribosomal protein L3 (348 aa)
RPS11ribosomal protein S11 (158 aa)
MRPS28mitochondrial ribosomal protein S28 (187 aa)
MRPL10mitochondrial ribosomal protein L10 (271 aa)
MRPS18Cmitochondrial ribosomal protein S18C (142 aa)
ICT1immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (206 aa)
MRPL39mitochondrial ribosomal protein L39 (353 aa)
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (274 aa)
MRPL13mitochondrial ribosomal protein L13 (178 aa)
DDX28DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (540 aa)
MRPL12mitochondrial ribosomal protein L12 (198 aa)
DAP3death associated protein 3; Involved in mediating interferon-gamma-induced cell death (398 aa)
MRPL52mitochondrial ribosomal protein L52 (123 aa)
MRPL55mitochondrial ribosomal protein L55 (164 aa)
MRPS18Amitochondrial ribosomal protein S18A (196 aa)
MRPS16mitochondrial ribosomal protein S16 (137 aa)
MRPL23mitochondrial ribosomal protein L23 (153 aa)
MRPS6mitochondrial ribosomal protein S6 (125 aa)
CALUcalumenin (323 aa)
MRPL42mitochondrial ribosomal protein L42 (142 aa)
MTHFD1methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (935 aa)
RPS15ribosomal protein S15 (145 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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